Klebsiella pneumoniae strain EuSCAPE_LU004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_LU004 is a Gram-negative, rod-shaped bacterium that is categorized as a facultative anaerobe and is chemoheterotrophic in its metabolic processes. This strain exhibits a unique cell arrangement, typically found in chains, pairs, or singles, and possesses mobility due to the presence of flagella. It thrives optimally at a temperature of 37°C, fitting within a mesophilic temperature range. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, and other Metazoa, indicating its broad ecological presence. Its biotic relationship is classified as free-living, but it is known to be pathogenic specifically to humans, where it can cause a range of health issues. These include bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and neonatal sepsis. Klebsiella pneumoniae strain EuSCAPE_LU004 does not sporulate and has a single replicon and a double membrane structure, typical of Gram-negative bacteria. The diverse health effects associated with this strain highlight its significant role in both human health and disease, emphasizing the importance of understanding its pathogenic mechanisms and potential environmental reservoirs. Its presence in various animal hosts suggests a complex ecological interaction that may facilitate its transmission and persistence in different environments. Understanding this strain's traits can inform public health strategies aimed at controlling infections it can cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_LU004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_LU004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_LU004 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4728 genes

Non-Coding Genes

291 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
molybdenum abc transporter substrate-binding proteinSAMEA3672956_00965Not AvailableNegative1023454 - 102422726966.2
membrane proteinSAMEA3672956_00966Not AvailableNegative1024370 - 10245195384.86
transcriptional regulator modeSAMEA3672956_00967Not AvailablePositive1024672 - 102546028236.9
putative molybdenum transport atp-binding protein modfSAMEA3672956_00968Not AvailablePositive1025528 - 102700053825.0
udp-galactose-4-epimeraseSAMEA3672956_00969Not AvailablePositive1027210 - 102822636992.9
galactose-1-phosphate uridylyltransferaseSAMEA3672956_00970Not AvailablePositive1028236 - 102928239610.3
galactokinaseSAMEA3672956_00971Not AvailablePositive1029285 - 103043341345.1
aldose 1-epimeraseSAMEA3672956_00972Not AvailablePositive1030427 - 103147038282.6
phosphoglycerate mutaseSAMEA3672956_00973Not AvailablePositive1031762 - 103251428319.5
2-keto-3-deoxy-d-arabino-heptulosonate-7- phosphate synthase i alphaSAMEA3672956_00974Not AvailableNegative1032588 - 103364037942.6

Displaying genes 1211 – 1220 of 5013 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total