Klebsiella pneumoniae strain EuSCAPE_RS076

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS076 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, primarily functioning as a chemoheterotroph. This strain typically forms chains, pairs, and singles in its cellular arrangement and possesses flagella, which contributes to its mobility. It thrives optimally at 37°C, fitting within the mesophilic temperature range. This bacterium is host-associated, demonstrating a free-living biotic relationship and interacting with a diverse array of hosts, including Homo sapiens (humans), Gallus gallus (chickens), various metazoans, plants (Viridiplantae), Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (domestic dogs), amphibians, and Equidae (horses). Klebsiella pneumoniae strain EuSCAPE_RS076 is notable for its pathogenicity in humans, being associated with a wide range of health effects. These include bacteremia, urinary tract infections, pneumonia, cystitis, intra-abdominal infections, liver abscesses, meningitis, wound infections, and more severe conditions such as sepsis and septicemia. The diversity of conditions linked to this strain underscores its clinical significance. The ecological insight from the data suggests that Klebsiella pneumoniae's adaptability to various hosts and environments, combined with its pathogenic potential, positions it as a critical player in both human health and the broader ecological context. Its capacity to thrive in diverse habitats and cause numerous infections highlights the importance of monitoring its prevalence and resistance patterns in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS076

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS076
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS076 genome assembly,

Gene Summary

Adenine Count

1217945 bp

Thymine Count

1222588 bp

Guanine Count

1626807 bp

Cytosine Count

1597022 bp

Genome Length

5664362 bp

Protein-coding Genes

5093 genes

Non-Coding Genes

301 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Head morphogenesis proteinSAMEA3721196_00318Not AvailablePositive304517 - 30541633674.3
EndzSAMEA3721196_00319Not AvailablePositive305516 - 30610322359.6
uncharacterised proteinSAMEA3721196_00320Not AvailablePositive306168 - 3063506665.28
Hypothetical proteinSAMEA3721196_00321Not AvailablePositive306363 - 30774851014.0
Capsid proteinSAMEA3721196_00322Not AvailablePositive307752 - 30818315075.9
Capsid proteinSAMEA3721196_00323Not AvailablePositive308195 - 30929240564.5
Hypothetical proteinSAMEA3721196_00324Not AvailablePositive309302 - 30959510293.8
Hypothetical proteinSAMEA3721196_00325Not AvailablePositive309598 - 30997812924.6
Hypothetical proteinSAMEA3721196_00326Not AvailablePositive309978 - 3101516673.88
Hypothetical proteinSAMEA3721196_00327Not AvailablePositive310151 - 31051313141.1

Displaying genes 41 – 50 of 5394 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total