Klebsiella pneumoniae strain EuSCAPE_SI026

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI026 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. It exhibits mobility due to the presence of flagella and typically exists in various arrangements, including chains, pairs, and singles. This strain thrives optimally at 37°C, indicating its mesophilic nature, and is associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and multiple other animal and plant species. The bacterium has significant pathogenic potential, being implicated in numerous health conditions such as bacteremia, urinary tract infections, pneumonia, and various forms of sepsis, among others. Notably, it is known for causing severe infections like pyogenic liver abscesses and neonatal sepsis. This wide spectrum of diseases underlines its relevance in clinical microbiology and public health. Ecologically, K. pneumoniae strain EuSCAPE_SI026 is classified as free-living, which suggests it can exist independently in the environment, yet it maintains a strong association with its hosts. The ability to infect a variety of hosts, including mammals, birds, and even plants, highlights its adaptability and potential for cross-species transmission. Understanding the ecological roles and pathogenic mechanisms of K. pneumoniae is crucial for managing infections and mitigating the risks associated with this versatile bacterium. Its presence in both human and animal hosts underscores the importance of surveillance and research to combat its impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI026

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI026
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI026 genome assembly,

Gene Summary

Adenine Count

1230299 bp

Thymine Count

1226679 bp

Guanine Count

1599343 bp

Cytosine Count

1652463 bp

Genome Length

5708784 bp

Protein-coding Genes

5054 genes

Non-Coding Genes

377 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gntr family transcriptional regulatorSAMEA3673043_04061Not AvailablePositive4270192 - 427062615110.1
nadh oxidoreductase hcrSAMEA3673043_04062Not AvailableNegative4270838 - 427180635792.9
hydroxylamine reductaseSAMEA3673043_04063Not AvailableNegative4271817 - 427346959963.0
surface proteinSAMEA3673043_04064Not AvailableNegative4273613 - 427451232509.4
aquaporinSAMEA3673043_04065Not AvailableNegative4274628 - 427532323705.3
old family atp-dependent endonucleaseSAMEA3673043_04066Not AvailablePositive4275743 - 427740163910.5
macrolide-specific efflux protein macaSAMEA3673043_04067Not AvailablePositive4277548 - 427866340725.5
macrolide export atp-binding/permease macbSAMEA3673043_04068Not AvailablePositive4278660 - 428060070136.5
cold shock protein cspdSAMEA3673043_04069Not AvailableNegative4280677 - 42808987887.33
atp-dependent clp protease adaptor protein clpsSAMEA3673043_04070Not AvailablePositive4281224 - 428154112205.7

Displaying genes 4191 – 4200 of 5431 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total