Klebsiella pneumoniae strain EuSCAPE_RO113

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RO113 is a Gram-negative bacterium that exhibits a rod shape and is known for its mobility, facilitated by the presence of flagella. This strain is classified as a chemoheterotroph and requires organic compounds for energy, thriving optimally at 37°C within a mesophilic temperature range. It has a unique cell arrangement characterized by chains, pairs, and singles, and is a facultative anaerobe, allowing it to survive in both aerobic and anaerobic environments. K. pneumoniae strain EuSCAPE_RO113 has significant implications for human health, being associated with a wide range of infections, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It is particularly concerning due to its role in neonatal sepsis and other severe conditions such as pyogenic liver abscesses and septicemia. This strain is free-living and has a diverse array of hosts, including various species within Homo sapiens, Gallus gallus, and several others across Metazoa and Viridiplantae. This broad host range highlights its ecological adaptability and potential for cross-species transmission. In summary, Klebsiella pneumoniae strain EuSCAPE_RO113 exemplifies a pathogenic microorganism with significant health impacts, demonstrating its versatility in both habitat and host interactions. Its presence in diverse ecological niches underlines the importance of monitoring this strain to understand its role in emerging infectious diseases and its potential for transmission across species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RO113

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RO113
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RO113 genome assembly,

Gene Summary

Adenine Count

1242545 bp

Thymine Count

1241073 bp

Guanine Count

1641607 bp

Cytosine Count

1632863 bp

Genome Length

5758088 bp

Protein-coding Genes

5159 genes

Non-Coding Genes

388 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transporterSAMEA3721041_03916Not AvailablePositive4111434 - 411304158547.3
benzoate 1,2-dioxygenaseSAMEA3721041_03917Not AvailablePositive4113078 - 411420242747.2
succinate-semialdehyde dehydrogenaseSAMEA3721041_03918Not AvailablePositive4114221 - 411566951409.5
flavodoxin reductases (ferredoxin-nadph reductases) family 1SAMEA3721041_03919Not AvailablePositive4115727 - 411669235519.2
pts system phosphoenolpyruvate-protein phosphotransferaseSAMEA3721041_03920Not AvailableNegative4116730 - 411923191820.4
putative fructose-like permease eiic subunit 2SAMEA3721041_03921Not AvailablePositive4119541 - 412061736969.7
pts system fructose-like transporter subunit iib 1SAMEA3721041_03922Not AvailablePositive4120638 - 412095811315.6
pyruvate formate-lyaseSAMEA3721041_03923Not AvailablePositive4121008 - 412330585871.9
pyruvate formate-lyase activating enzymeSAMEA3721041_03924Not AvailablePositive4123271 - 412414632830.8
pts system fructose transporter subunit iibSAMEA3721041_03925Not AvailablePositive4124162 - 412450312689.5

Displaying genes 4081 – 4090 of 5547 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total