Klebsiella pneumoniae strain EuSCAPE_UK133

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK133 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing organic compounds as a chemoheterotrophic energy source. This strain is capable of mobility due to the presence of flagella and typically forms chains, pairs, or singles in its cellular arrangement. It thrives optimally at 37°C, falling within the mesophilic temperature range. The strain is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other metazoans and plant species. Klebsiella pneumoniae is known for its significant health implications in humans, being implicated in conditions such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its pathogenicity is notably linked to its ability to cause severe infections, including sepsis and neonatal sepsis, as well as less common ailments such as emphysematous pyelonephritis and endogenous endophthalmitis. Klebsiella pneumoniae strain EuSCAPE_UK133 demonstrates a biotic relationship that allows it to exist freely in various environments while still maintaining the potential to infect a wide range of hosts. The ability to cause infections in both human and animal hosts underscores the ecological versatility and pathogenic potential of this strain, highlighting its significance in clinical microbiology and public health. The presence of a single replicon and two membranes further supports its classification within the Enterobacteriaceae family, contributing to its metabolic and pathogenic characteristics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK133

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK133
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK133 genome assembly,

Gene Summary

Adenine Count

1237216 bp

Thymine Count

1236723 bp

Guanine Count

1639284 bp

Cytosine Count

1621536 bp

Genome Length

5734759 bp

Protein-coding Genes

4981 genes

Non-Coding Genes

185 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3673097_01721Not AvailableNegative1871990 - 18722449490.27
Hypothetical proteinSAMEA3673097_01722Not AvailableNegative1872237 - 187260213363.3
uncharacterised proteinSAMEA3673097_01723Not AvailableNegative1872603 - 18728278781.49
uncharacterised proteinSAMEA3673097_01724Not AvailableNegative1872830 - 18729373974.87
uncharacterised proteinSAMEA3673097_01725Not AvailableNegative1873010 - 187342315506.5
Putative transcriptional regulatorSAMEA3673097_01726Not AvailableNegative1873587 - 187426124895.6
uncharacterised proteinSAMEA3673097_01727Not AvailablePositive1874637 - 187539829228.9
Hypothetical proteinSAMEA3673097_01728Not AvailablePositive1875624 - 187647529741.9
Putative replication protein dnacSAMEA3673097_01729Not AvailablePositive1876487 - 187736532957.9
Putative helicaseSAMEA3673097_01730Not AvailablePositive1877362 - 187874150709.6

Displaying genes 11 – 20 of 5166 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total