Klebsiella pneumoniae strain EuSCAPE_UK090

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK090 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It has a facultative anaerobic metabolism, functioning as a chemoheterotroph and thriving optimally at 37°C within a mesophilic temperature range. The organism is typically found in host-associated habitats, indicating its relationship with various hosts, including Homo sapiens, Gallus gallus, and several other species across the animal and plant kingdoms. This strain is known to form chains, pairs, and singles in its cellular arrangement and has a characteristic biotic relationship as a free-living organism. Klebsiella pneumoniae is not capable of sporulation and possesses a single replicon alongside a dual membrane structure. Pathogenicity is a significant aspect of this strain, as it is associated with a wide array of health complications in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. These health effects underline its role as a notable human pathogen. The strain's ability to cause diverse infections, such as liver abscesses and meningitis, emphasizes its clinical relevance and the challenges it poses in healthcare settings. Ecologically, the versatility of Klebsiella pneumoniae strain EuSCAPE_UK090 across different hosts illustrates its adaptability and potential impact on both human health and environmental microbiomes. Understanding its pathogenic mechanisms and host interactions is crucial for addressing the public health challenges it presents.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK090

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK090
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK090 genome assembly,

Gene Summary

Adenine Count

1162903 bp

Thymine Count

1156314 bp

Guanine Count

1542491 bp

Cytosine Count

1571349 bp

Genome Length

5433057 bp

Protein-coding Genes

4886 genes

Non-Coding Genes

283 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Gp10SAMEA3673055_00916Not AvailableNegative978159 - 97860816636.9
Head-tail connector iiSAMEA3673055_00917Not AvailableNegative978955 - 97928112406.7
Head-tail connector iSAMEA3673055_00918Not AvailableNegative979281 - 9794787234.66
Major head subunitSAMEA3673055_00919Not AvailableNegative979521 - 98073843776.4
Head maturation proteaseSAMEA3673055_00920Not AvailableNegative980748 - 98159629542.1
Portal proteinSAMEA3673055_00921Not AvailableNegative981609 - 98291648718.1
Terminase large subunit-like proteinSAMEA3673055_00922Not AvailableNegative982916 - 98465864841.7
Terminase small subunitSAMEA3673055_00923Not AvailableNegative984612 - 98507616943.5
Hnh endonucleaseSAMEA3673055_00924Not AvailableNegative985259 - 98560013166.9
Hypothetical proteinSAMEA3673055_00925Not AvailableNegative985656 - 9859018997.61

Displaying genes 11 – 20 of 5169 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total