Klebsiella pneumoniae strain EuSCAPE_UK127

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK127 is a Gram-negative, rod-shaped bacterium exhibiting a facultative anaerobic metabolism and belonging to the chemoheterotroph category. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically forms chains, pairs, or singles in its cell arrangement. It thrives optimally at 37°C, indicating a mesophilic nature. This strain is notably associated with various hosts, including Homo sapiens and other species such as Gallus gallus, Danio rerio, and Canis lupus familiaris. It is recognized for its pathogenic potential in humans, being implicated in multiple health issues, such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other significant health effects include sepsis and neonatal sepsis, underscoring the strain's relevance in clinical settings. Klebsiella pneumoniae EuSCAPE_UK127 is nonsporulating and possesses a single replicon contained within two membranes, typical of Gram-negative bacteria. Its biotic relationships suggest it can exist freely in the environment while also adapting to exploit various host organisms. The ecological insight drawn from the data indicates that Klebsiella pneumoniae strain EuSCAPE_UK127 plays a dual role, acting both as a free-living organism in diverse environments and as a significant pathogen in multiple hosts, particularly humans. This versatility underscores the importance of monitoring such strains in both clinical and environmental microbiology contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK127

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK127
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK127 genome assembly,

Gene Summary

Adenine Count

1193257 bp

Thymine Count

1192600 bp

Guanine Count

1597303 bp

Cytosine Count

1589430 bp

Genome Length

5572590 bp

Protein-coding Genes

5006 genes

Non-Coding Genes

230 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3673091_02225Not AvailablePositive2367218 - 23674217431.76
HolinSAMEA3673091_02226Not AvailablePositive2367425 - 23676408077.99
LysozymeSAMEA3673091_02227Not AvailablePositive2367621 - 236813018464.4
AttrNot AvailableNot AvailablePositive2367848 - 2367862Not Available
Lysb family lysis regulatory proteinSAMEA3673091_02228Not AvailablePositive2368135 - 236856315933.2
Tail proteinSAMEA3673091_02229Not AvailablePositive2368659 - 236909015912.8
Virion morphogenesis proteinSAMEA3673091_02230Not AvailablePositive2369083 - 236953517610.3
AttlNot AvailableNot AvailablePositive2370084 - 2370095Not Available
Putative tail proteinSAMEA3673091_02231Not AvailableNegative2370472 - 237294391706.1
Tail assembly proteinSAMEA3673091_02232Not AvailableNegative2372930 - 237332514782.9

Displaying genes 71 – 80 of 5236 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total