Klebsiella pneumoniae strain EuSCAPE_UK127

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK127 is a Gram-negative, rod-shaped bacterium exhibiting a facultative anaerobic metabolism and belonging to the chemoheterotroph category. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically forms chains, pairs, or singles in its cell arrangement. It thrives optimally at 37°C, indicating a mesophilic nature. This strain is notably associated with various hosts, including Homo sapiens and other species such as Gallus gallus, Danio rerio, and Canis lupus familiaris. It is recognized for its pathogenic potential in humans, being implicated in multiple health issues, such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Other significant health effects include sepsis and neonatal sepsis, underscoring the strain's relevance in clinical settings. Klebsiella pneumoniae EuSCAPE_UK127 is nonsporulating and possesses a single replicon contained within two membranes, typical of Gram-negative bacteria. Its biotic relationships suggest it can exist freely in the environment while also adapting to exploit various host organisms. The ecological insight drawn from the data indicates that Klebsiella pneumoniae strain EuSCAPE_UK127 plays a dual role, acting both as a free-living organism in diverse environments and as a significant pathogen in multiple hosts, particularly humans. This versatility underscores the importance of monitoring such strains in both clinical and environmental microbiology contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK127

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK127
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK127 genome assembly,

Gene Summary

Adenine Count

1193257 bp

Thymine Count

1192600 bp

Guanine Count

1597303 bp

Cytosine Count

1589430 bp

Genome Length

5572590 bp

Protein-coding Genes

5006 genes

Non-Coding Genes

230 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alkanesulfonates abc transporter atp-binding protein / sulfonate abc transporterSAMEA3673091_00304Not AvailablePositive329446 - 33021928146.5
tonb-dependent siderophore receptorSAMEA3673091_00305Not AvailableNegative330641 - 33271375556.5
transportSAMEA3673091_00306Not AvailablePositive333219 - 33404030036.5
iron compound permease protein of abc transporter familySAMEA3673091_00307Not AvailablePositive334037 - 33506234802.3
permease of ferrichrome abc transporterSAMEA3673091_00308Not AvailablePositive335059 - 33611136695.7
putative iron compound abc transport system periplasmic binding componentSAMEA3673091_00309Not AvailablePositive336125 - 33707835002.0
putative transcriptional regulatorSAMEA3673091_00310Not AvailablePositive337075 - 33797732681.8
amino acid abc transporter periplasmic amino acid-binding proteinSAMEA3673091_00311Not AvailablePositive338070 - 33883727671.1
amino acid abc transporterSAMEA3673091_00312Not AvailablePositive338901 - 33966528344.2
histidine abc transporter atp-binding proteinSAMEA3673091_00313Not AvailablePositive339652 - 34037426332.2

Displaying genes 471 – 480 of 5236 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total