Klebsiella pneumoniae strain EuSCAPE_UK119

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK119 is a significant Gram-negative, rod-shaped bacterium known for its pathogenicity in humans. This strain is a facultative anaerobe and a chemoheterotroph, suggesting its ability to thrive in varied oxygen environments while deriving energy from organic compounds. The typical morphology includes arrangements in chains, pairs, and singles, indicating a versatile growth pattern. This strain is notable for its mobility, attributed to the presence of flagella. It thrives optimally at 37°C, falling within the mesophilic temperature range, which aligns with the typical human body temperature, suggesting its adaptation to the human host. With a single replicon and two membranes, Klebsiella pneumoniae exhibits characteristics common to many bacteria in the Enterobacteriaceae family. Klebsiella pneumoniae strain EuSCAPE_UK119 has a diverse host range, affecting various organisms including Homo sapiens, Gallus gallus, and several other metazoans and vertebrates. Its biotic relationship is classified as free-living, indicating a potential environmental presence. The health implications of this strain are serious, as it has been linked to a multitude of infections, such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The range of infections underscores its pathogenic potential and highlights the importance of monitoring this strain in clinical settings. In summary, Klebsiella pneumoniae strain EuSCAPE_UK119 exemplifies the adaptability and pathogenicity of certain bacteria, underlining the need for ongoing research and vigilance in understanding its ecological and health impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK119

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK119
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK119 genome assembly,

Gene Summary

Adenine Count

1185149 bp

Thymine Count

1183612 bp

Guanine Count

1607418 bp

Cytosine Count

1565547 bp

Genome Length

5541726 bp

Protein-coding Genes

4998 genes

Non-Coding Genes

237 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Major tail shaft subunitSAMEA3673083_03377Not AvailablePositive3555103 - 355556416040.3
Putative tail assembly chaperoneSAMEA3673083_03378Not AvailablePositive3555622 - 355598713283.0
Tail length tape measure protein hSAMEA3673083_03379Not AvailablePositive3556220 - 3559555117911.0
Minor tail protein mSAMEA3673083_03380Not AvailablePositive3559555 - 355989312791.1
Minor tail protein lSAMEA3673083_03381Not AvailablePositive3559890 - 356064528082.8
Minor tail proteinSAMEA3673083_03382Not AvailablePositive3560647 - 356135727640.7
serine protease do-like htraSAMEA3673083_03383Not AvailablePositive3561418 - 356209524810.5
Tail assembly protein iSAMEA3673083_03384Not AvailablePositive3562142 - 356273220722.4
Gp21SAMEA3673083_03385Not AvailablePositive3562795 - 3574011397964.0
Tail fibers proteinSAMEA3673083_03386Not AvailablePositive3574073 - 357556953063.6

Displaying genes 171 – 180 of 5235 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total