Klebsiella pneumoniae strain EuSCAPE_UK099

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_UK099 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. It is a chemoheterotroph, deriving energy from organic compounds, and typically resides in host-associated environments. This strain is capable of mobility, possessing flagella, and it typically arranges itself in chains, pairs, or as singles. Optimal growth for EuSCAPE_UK099 occurs at a temperature of 37°C, placing it within the mesophilic range. It has a single replicon and is characterized by a double-membrane structure. This bacterium is classified as free-living and has a diverse range of hosts, including various species within Homo sapiens, Gallus gallus, Metazoa, Viridiplantae, and several others such as Canis lupus familiaris and Equidae. Klebsiella pneumoniae strain EuSCAPE_UK099 is associated with numerous health effects, particularly in humans, where it can cause conditions such as bacteremia, urinary tract infections, pneumonia, and various abdominal infections, among others. Its pathogenicity in humans highlights its importance as a significant opportunistic pathogen. The ecological implications of Klebsiella pneumoniae strain EuSCAPE_UK099 underscore its adaptability and potential for transmission across diverse species. Its capacity to inhabit various hosts and the range of diseases it can cause indicate its role in both human health and environmental microbiology, emphasizing the need for continued study of its pathogenic mechanisms and ecological interactions.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_UK099

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_UK099
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_UK099 genome assembly,

Gene Summary

Adenine Count

1135690 bp

Thymine Count

1131167 bp

Guanine Count

1514435 bp

Cytosine Count

1535671 bp

Genome Length

5316963 bp

Protein-coding Genes

4738 genes

Non-Coding Genes

286 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
HolinSAMEA3673063_00279Not AvailableNegative299139 - 2993638271.87
uncharacterised proteinSAMEA3673063_00280Not AvailablePositive299660 - 2998517503.47
Hypothetical proteinSAMEA3673063_00281Not AvailableNegative300367 - 30098123622.4
NinzSAMEA3673063_00282Not AvailableNegative300978 - 3011607136.49
Putative recombination endonucleaseSAMEA3673063_00283Not AvailableNegative301342 - 30229237028.1
Dna n-6-adenine-methyltransferaseSAMEA3673063_00284Not AvailableNegative302425 - 30297320570.7
Hypothetical proteinSAMEA3673063_00285Not AvailableNegative303438 - 3036568074.42
Hypothetical proteinSAMEA3673063_00286Not AvailableNegative303649 - 30493247263.2
Ead-like proteinSAMEA3673063_00287Not AvailableNegative305111 - 30571922685.6
Hypothetical proteinSAMEA3673063_00288Not AvailableNegative305712 - 3059187425.21

Displaying genes 31 – 40 of 5024 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total