Klebsiella pneumoniae strain EuSCAPE_UK086

Klebsiella pneumoniae strain EuSCAPE_UK086 is a pathogenic, Gram-negative, rod-shaped bacterium that is a member of the Enterobacteriaceae family. This strain exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph, and thrives optimally at 37°C, fitting within the mesophilic temperature range. Its cellular arrangement can be characterized as chains, pairs, or singles, and it possesses flagella, which contributes to its mobility. The strain is notably associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other vertebrate and invertebrate species. This broad host range highlights its ecological adaptability and potential for transmission across different environments. Klebsiella pneumoniae strain EuSCAPE_UK086 is recognized for its significant health impacts, being implicated in numerous serious infections such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain's pathogenicity is particularly concerning in humans, given its association with severe conditions like sepsis and neonatal sepsis. Despite its status as a free-living organism, the strain is nonsporulating, indicating that it does not form spores as a means of survival under adverse conditions. This trait may influence its ecological niche and interactions with hosts. The presence of two membranes further underscores its classification as a Gram-negative bacterium, which is relevant to its antibiotic resistance profiles and interactions with the host immune system. Overall, Klebsiella pneumoniae strain EuSCAPE_UK086 exemplifies the complex interplay between microbial organisms and their hosts, as well as the challenges they pose in clinical settings due to their pathogenicity and adaptability.