Klebsiella pneumoniae strain EuSCAPE_SI022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI022 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and ability to thrive optimally at 37°C, placing it within the mesophilic temperature range. This strain is notable for its mobility, facilitated by the presence of flagella, and exhibits a unique cell arrangement that includes chains, pairs, and singles. As a chemoheterotroph, EuSCAPE_SI022 utilizes organic compounds as its energy source, and it is primarily associated with a variety of hosts, including Homo sapiens, various birds, mammals, and plants. Its biotic relationship is classified as free-living, indicating its capacity to exist independently in the environment. This strain is associated with a broad spectrum of health effects in humans, including but not limited to bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The pathogenicity of Klebsiella pneumoniae highlights its significant role as a human pathogen, contributing to severe conditions such as sepsis and neonatal infections. Given its diverse host range and the serious health implications associated with infections caused by this strain, Klebsiella pneumoniae EuSCAPE_SI022 serves as a critical point of study in understanding the dynamics of microbial pathogenicity and the potential for cross-species transmission. The insights gained from studying this strain can inform public health strategies aimed at managing and preventing infections, particularly in healthcare settings where antibiotic resistance is a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI022 genome assembly,

Gene Summary

Adenine Count

1118653 bp

Thymine Count

1113163 bp

Guanine Count

1492220 bp

Cytosine Count

1511374 bp

Genome Length

5235410 bp

Protein-coding Genes

4748 genes

Non-Coding Genes

127 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2-component transcriptional regulatorSAMEA3673039_00022Not AvailableNegative20023 - 2063423199.9
arac family transcriptional regulatorSAMEA3673039_00023Not AvailablePositive20930 - 2187135517.6
gluconate permeaseSAMEA3673039_00024Not AvailableNegative21898 - 2326246962.6
hydroxypyruvate isomeraseSAMEA3673039_00025Not AvailableNegative23320 - 2410229362.0
ribulose-5-phosphate 4-epimeraseSAMEA3673039_00026Not AvailableNegative24107 - 2472722627.1
ygbk domain proteinSAMEA3673039_00027Not AvailableNegative24720 - 2598545053.9
ygbjSAMEA3673039_00028Not AvailableNegative25997 - 2689930509.0
deor family transcriptional regulatorSAMEA3673039_00029Not AvailablePositive27161 - 2792227339.8
beta-lactamaseSAMEA3673039_00030Not AvailableNegative27943 - 2880331178.8
putative k+ transporting atpase, kdpc subunitSAMEA3673039_00031Not AvailablePositive29101 - 293619396.35

Displaying genes 71 – 80 of 4875 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total