Klebsiella pneumoniae strain EuSCAPE_SI022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI022 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and ability to thrive optimally at 37°C, placing it within the mesophilic temperature range. This strain is notable for its mobility, facilitated by the presence of flagella, and exhibits a unique cell arrangement that includes chains, pairs, and singles. As a chemoheterotroph, EuSCAPE_SI022 utilizes organic compounds as its energy source, and it is primarily associated with a variety of hosts, including Homo sapiens, various birds, mammals, and plants. Its biotic relationship is classified as free-living, indicating its capacity to exist independently in the environment. This strain is associated with a broad spectrum of health effects in humans, including but not limited to bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The pathogenicity of Klebsiella pneumoniae highlights its significant role as a human pathogen, contributing to severe conditions such as sepsis and neonatal infections. Given its diverse host range and the serious health implications associated with infections caused by this strain, Klebsiella pneumoniae EuSCAPE_SI022 serves as a critical point of study in understanding the dynamics of microbial pathogenicity and the potential for cross-species transmission. The insights gained from studying this strain can inform public health strategies aimed at managing and preventing infections, particularly in healthcare settings where antibiotic resistance is a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI022 genome assembly,

Gene Summary

Adenine Count

1118653 bp

Thymine Count

1113163 bp

Guanine Count

1492220 bp

Cytosine Count

1511374 bp

Genome Length

5235410 bp

Protein-coding Genes

4748 genes

Non-Coding Genes

127 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
fes assembly protein iscxSAMEA3673039_01763Not AvailableNegative1878781 - 18789817745.94
ferredoxinSAMEA3673039_01764Not AvailableNegative1878983 - 187931812342.4
chaperone protein hscaSAMEA3673039_01765Not AvailableNegative1879320 - 188117065399.2
chaperone protein hscbSAMEA3673039_01766Not AvailableNegative1881186 - 188170119825.4
iron binding protein isca for iron-sulfur cluster assemblySAMEA3673039_01767Not AvailableNegative1881776 - 188209911449.5
iron-sulfur cluster assembly scaffold protein iscuSAMEA3673039_01768Not AvailableNegative1882117 - 188250313807.3
cysteine desulfuraseSAMEA3673039_01769Not AvailableNegative1882530 - 188374445059.1
iron-sulfur cluster regulator iscrSAMEA3673039_01770Not AvailableNegative1883923 - 188441417551.9
trna:cm32/um32 methyltransferaseSAMEA3673039_01771Not AvailableNegative1884649 - 188538326799.4
inositol-1-monophosphataseSAMEA3673039_01772Not AvailablePositive1885504 - 188630729322.0

Displaying genes 1811 – 1820 of 4875 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total