Klebsiella pneumoniae strain EuSCAPE_SI014

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI014 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophic energy sources. It is characterized by its mobility, facilitated by the presence of flagella, and typically occurs in various arrangements including chains, pairs, and singles. This strain thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The habitat of EuSCAPE_SI014 is host-associated, indicating its presence in biological environments closely linked to various hosts. It has been identified in Homo sapiens and other species such as Gallus gallus, Canis lupus familiaris, and several Metazoa and Viridiplantae, reflecting its broad ecological niche and potential for cross-species transmission. EuSCAPE_SI014 is known for its pathogenicity in humans, being associated with a wide range of health complications. These include bacteremia, pneumonia, urinary tract infections, and even severe conditions like septicemia and neonatal sepsis. The bacterium's ability to cause such diverse infections emphasizes its clinical significance and the need for vigilant monitoring in healthcare settings. Given its free-living nature and extensive host range, Klebsiella pneumoniae strain EuSCAPE_SI014 plays an important role in both human health and ecological interactions. Its presence across multiple hosts suggests a complex relationship with its environment, where it can act as both a commensal organism and a pathogen, highlighting the dynamic interplay between microbial life and host health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI014

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI014
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI014 genome assembly,

Gene Summary

Adenine Count

1225102 bp

Thymine Count

1223284 bp

Guanine Count

1630671 bp

Cytosine Count

1623484 bp

Genome Length

5702541 bp

Protein-coding Genes

5117 genes

Non-Coding Genes

370 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
galactoside permeaseSAMEA3673031_05012Not AvailableNegative5247085 - 524833846569.9
beta-d-galactosidaseSAMEA3673031_05013Not AvailableNegative5248390 - 5251464116328.0
lac repressorSAMEA3673031_05014Not AvailableNegative5251586 - 525273441310.7
putative alginate lyaseSAMEA3673031_05015Not AvailablePositive5253129 - 525413936409.1
isec8 transposaseSAMEA3673031_05016Not AvailableNegative5255091 - 525538410906.6
iron(iii) dicitrate abc transporter, atp-binding protein feceSAMEA3673031_05017Not AvailableNegative5255483 - 525625028124.4
iron(iii) dicitrate transport system permease protein fecdSAMEA3673031_05018Not AvailableNegative5256251 - 525720734212.8
fe(3+) dicitrate transport system permease protein feccSAMEA3673031_05019Not AvailableNegative5257204 - 525820234921.0
periplasmic binding proteinSAMEA3673031_05020Not AvailableNegative5258199 - 525910132954.8
fe(3+) dicitrate transport protein fecaSAMEA3673031_05021Not AvailableNegative5259146 - 526147085310.3

Displaying genes 5091 – 5100 of 5487 in total

Metabolites

1247 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1247 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total