Klebsiella pneumoniae strain EuSCAPE_SI014

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI014 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophic energy sources. It is characterized by its mobility, facilitated by the presence of flagella, and typically occurs in various arrangements including chains, pairs, and singles. This strain thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The habitat of EuSCAPE_SI014 is host-associated, indicating its presence in biological environments closely linked to various hosts. It has been identified in Homo sapiens and other species such as Gallus gallus, Canis lupus familiaris, and several Metazoa and Viridiplantae, reflecting its broad ecological niche and potential for cross-species transmission. EuSCAPE_SI014 is known for its pathogenicity in humans, being associated with a wide range of health complications. These include bacteremia, pneumonia, urinary tract infections, and even severe conditions like septicemia and neonatal sepsis. The bacterium's ability to cause such diverse infections emphasizes its clinical significance and the need for vigilant monitoring in healthcare settings. Given its free-living nature and extensive host range, Klebsiella pneumoniae strain EuSCAPE_SI014 plays an important role in both human health and ecological interactions. Its presence across multiple hosts suggests a complex relationship with its environment, where it can act as both a commensal organism and a pathogen, highlighting the dynamic interplay between microbial life and host health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI014

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI014
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI014 genome assembly,

Gene Summary

Adenine Count

1225102 bp

Thymine Count

1223284 bp

Guanine Count

1630671 bp

Cytosine Count

1623484 bp

Genome Length

5702541 bp

Protein-coding Genes

5117 genes

Non-Coding Genes

370 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phage shock protein dSAMEA3673031_03716Not AvailableNegative3858736 - 38589547807.01
phage shock protein cSAMEA3673031_03717Not AvailableNegative3858983 - 385934213350.6
phage shock protein bSAMEA3673031_03718Not AvailableNegative3859342 - 38595668761.7
phage shock protein pspaSAMEA3673031_03719Not AvailableNegative3859622 - 386029025445.2
psp operon transcriptional activatorSAMEA3673031_03720Not AvailablePositive3860458 - 386143236426.8
transporterSAMEA3673031_03721Not AvailableNegative3861423 - 386281448322.4
amidohydrolase family proteinSAMEA3673031_03722Not AvailableNegative3862840 - 386400942503.8
arac family transcriptional regulatorSAMEA3673031_03723Not AvailablePositive3864181 - 386649088322.3
transcriptional regulatorSAMEA3673031_03724Not AvailableNegative3866469 - 386729931233.2
nucleoside-diphosphate-sugar epimeraseSAMEA3673031_03725Not AvailablePositive3867410 - 386831532057.0

Displaying genes 3821 – 3830 of 5487 in total

Metabolites

1247 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1247 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total