Klebsiella pneumoniae strain EuSCAPE_SI014

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI014 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophic energy sources. It is characterized by its mobility, facilitated by the presence of flagella, and typically occurs in various arrangements including chains, pairs, and singles. This strain thrives optimally at a temperature of 37°C, placing it within the mesophilic temperature range. The habitat of EuSCAPE_SI014 is host-associated, indicating its presence in biological environments closely linked to various hosts. It has been identified in Homo sapiens and other species such as Gallus gallus, Canis lupus familiaris, and several Metazoa and Viridiplantae, reflecting its broad ecological niche and potential for cross-species transmission. EuSCAPE_SI014 is known for its pathogenicity in humans, being associated with a wide range of health complications. These include bacteremia, pneumonia, urinary tract infections, and even severe conditions like septicemia and neonatal sepsis. The bacterium's ability to cause such diverse infections emphasizes its clinical significance and the need for vigilant monitoring in healthcare settings. Given its free-living nature and extensive host range, Klebsiella pneumoniae strain EuSCAPE_SI014 plays an important role in both human health and ecological interactions. Its presence across multiple hosts suggests a complex relationship with its environment, where it can act as both a commensal organism and a pathogen, highlighting the dynamic interplay between microbial life and host health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI014

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI014
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI014 genome assembly,

Gene Summary

Adenine Count

1225102 bp

Thymine Count

1223284 bp

Guanine Count

1630671 bp

Cytosine Count

1623484 bp

Genome Length

5702541 bp

Protein-coding Genes

5117 genes

Non-Coding Genes

370 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pilus assembly proteinSAMEA3673031_03192Not AvailableNegative3290929 - 329172929736.8
peptidoglycan synthetaseSAMEA3673031_03193Not AvailablePositive3291848 - 329440693429.2
adp compounds hydrolase nudeSAMEA3673031_03194Not AvailableNegative3294460 - 329502021141.4
igaaSAMEA3673031_03195Not AvailablePositive3295341 - 329747079513.3
putative hydrolase with phophatase-like domainSAMEA3673031_03196Not AvailablePositive3297531 - 329821426076.0
rna-binding s4 domain-containing proteinSAMEA3673031_03197Not AvailablePositive3298211 - 329861215651.0
33 kda chaperonin (heat shock protein 33) (hsp33)SAMEA3673031_03198Not AvailablePositive3298637 - 329951532378.2
phosphoenolpyruvate carboxykinaseSAMEA3673031_03199Not AvailablePositive3299876 - 330149859580.5
osmolarity sensory histidine kinase envzSAMEA3673031_03200Not AvailableNegative3301576 - 330293150517.4
osmolarity response regulatorSAMEA3673031_03201Not AvailableNegative3302928 - 330364727355.3

Displaying genes 3351 – 3360 of 5487 in total

Metabolites

1247 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1247 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total