Klebsiella pneumoniae strain EuSCAPE_SI004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SI004 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans and a range of other hosts, including various animals and plants. This strain is classified as a chemoheterotroph and demonstrates facultative anaerobic metabolism, allowing it to thrive in diverse environments associated with living hosts. The organism is characterized by its ability to form chains, pairs, or exist as single cells, and it possesses flagella, which contributes to its mobility. EuSCAPE_SI004 has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. It features a cellular organization of one replicon and two membranes, typical of Gram-negative bacteria. Klebsiella pneumoniae is associated with several serious health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It is also involved in conditions such as liver abscesses, meningitis, and sepsis, highlighting its role as a significant pathogen in clinical settings. Notably, it can cause infections in neonates, as evidenced by its involvement in early onset neonatal sepsis. From an ecological perspective, Klebsiella pneumoniae strain EuSCAPE_SI004's free-living biotic relationship suggests its adaptability to various host environments, which may facilitate its transmission and persistence in both human and non-human populations. This adaptability poses challenges for public health, as the bacteria can easily spread and cause infections across a range of hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SI004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SI004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SI004 genome assembly,

Gene Summary

Adenine Count

1165134 bp

Thymine Count

1162426 bp

Guanine Count

1564958 bp

Cytosine Count

1567765 bp

Genome Length

5460283 bp

Protein-coding Genes

4939 genes

Non-Coding Genes

266 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative alpha-galactosidases/6-phospho-beta-glucosidasesSAMEA3673021_03750Not AvailablePositive3933951 - 393526448434.1
transcriptional repressor tyrrSAMEA3673021_03751Not AvailablePositive3935437 - 393697857402.5
protein abrbSAMEA3673021_03752Not AvailablePositive3937080 - 393813237502.0
thiol peroxidaseSAMEA3673021_03753Not AvailableNegative3938203 - 393870917544.9
l-ala-d/l-glu epimeraseSAMEA3673021_03754Not AvailablePositive3938812 - 393977734788.1
gamma-d-glutamyl-meso-diaminopimelate amidaseSAMEA3673021_03755Not AvailableNegative3939774 - 394048125617.2
periplasmic murein peptide-binding protein mppaSAMEA3673021_03756Not AvailablePositive3940667 - 394228359662.9
glyoxalaseSAMEA3673021_03757Not AvailableNegative3942451 - 394283714550.6
uncharacterised proteinSAMEA3673021_03758Not AvailablePositive3943068 - 394390131739.4
lysr family transcriptional regulatorSAMEA3673021_03759Not AvailableNegative3944026 - 394491032941.7

Displaying genes 3861 – 3870 of 5205 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total