Klebsiella pneumoniae strain EuSCAPE_SC031

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SC031 is a rod-shaped, Gram-negative bacterium that is classified as a facultative anaerobe. This organism exhibits a range of cellular arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. It thrives optimally at 37°C, fitting within the mesophilic temperature range. The strain has a single replicon and a double membrane structure, typical of Gram-negative bacteria. As a chemoheterotroph, Klebsiella pneumoniae strain EuSCAPE_SC031 derives energy from organic compounds, and it is primarily host-associated, exhibiting a free-living biotic relationship. This bacterium has a wide host range, infecting various species, including Homo sapiens (humans), Gallus gallus (chickens), and multiple others across the animal kingdom, such as Canis lupus familiaris (domestic dogs) and Sus scrofa (pigs), as well as plants. Klebsiella pneumoniae is notable for its pathogenicity in humans, being linked to a variety of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is responsible for conditions such as pyogenic liver abscesses and neonatal sepsis, highlighting its clinical significance. The ecological insight from Klebsiella pneumoniae strain EuSCAPE_SC031 is its ability to adapt to various hosts and environments, facilitating its survival and transmission. This adaptability may contribute to its role in both environmental microbiomes and clinical settings, where it poses significant health risks to humans and other animals.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SC031

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SC031
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SC031 genome assembly,

Gene Summary

Adenine Count

1289657 bp

Thymine Count

1280223 bp

Guanine Count

1667146 bp

Cytosine Count

1678340 bp

Genome Length

5915366 bp

Protein-coding Genes

5215 genes

Non-Coding Genes

223 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-arabinose 5-phosphate isomeraseSAMEA3673004_03217Not AvailablePositive3403360 - 340434635115.8
3-deoxy-d-manno-octulosonate 8-phosphate phosphataseSAMEA3673004_03218Not AvailablePositive3404361 - 340492720402.7
lipopolysaccharide exporter periplasmic proteinSAMEA3673004_03219Not AvailablePositive3404924 - 340549921662.7
lpta, protein essential for lps transport across the periplasmSAMEA3673004_03220Not AvailablePositive3405468 - 340601319863.8
lipopolysaccharide abc transporterSAMEA3673004_03221Not AvailablePositive3406020 - 340674526844.4
rna polymerase sigma-54 factor rponSAMEA3673004_03222Not AvailablePositive3406793 - 340822653927.9
ribosome hibernation protein yhbhSAMEA3673004_03223Not AvailablePositive3408249 - 340853610760.0
pts system transporter subunit iia-like nitrogen-regulatory protein ptsnSAMEA3673004_03224Not AvailablePositive3408607 - 340909517705.3
p-loop-containing kinaseSAMEA3673004_03225Not AvailablePositive3409141 - 340999532543.2
phosphocarrier proteinSAMEA3673004_03226Not AvailablePositive3409992 - 34102649807.75

Displaying genes 3231 – 3240 of 5438 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total