Klebsiella pneumoniae strain EuSCAPE_SC030

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SC030 is a clinically significant Gram-negative bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain typically exhibits a rod shape and can be found in various cell arrangements, including chains, pairs, and singles. It possesses flagella, which contribute to its mobility, and thrives optimally at 37°C, placing it within the mesophilic temperature range. The bacterium has a single replicon and is encased in two membranes, a common feature among Gram-negative organisms. EuSCAPE_SC030 is notably associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and plants, indicating its adaptability and potential ecological versatility. Its pathogenicity is primarily linked to humans, where it can cause a spectrum of serious health effects, such as bacteremia, urinary tract infections, pneumonia, and several other severe conditions including sepsis and meningitis. The presence of this strain in diverse environments, including free-living conditions and its ability to infect multiple hosts, highlights its ecological significance and potential for zoonotic transmission. This adaptability and pathogenic capability underscore the importance of monitoring Klebsiella pneumoniae in clinical and environmental contexts, particularly given its association with significant health burdens. Understanding the traits and behaviors of strains like EuSCAPE_SC030 can inform strategies for prevention and treatment of infections, as well as enhance our knowledge of microbial interactions in various ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SC030

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SC030
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SC030 genome assembly,

Gene Summary

Adenine Count

1245434 bp

Thymine Count

1241804 bp

Guanine Count

1630732 bp

Cytosine Count

1626086 bp

Genome Length

5744056 bp

Protein-coding Genes

5186 genes

Non-Coding Genes

366 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Baseplate wedge proteinSAMEA3673003_00322Not AvailablePositive302409 - 30360840933.2
Hypothetical proteinSAMEA3673003_00323Not AvailablePositive303605 - 30438128978.3
Putative tail fiber proteinSAMEA3673003_00324Not AvailablePositive304381 - 30528628788.5
uncharacterised proteinSAMEA3673003_00325Not AvailablePositive305286 - 3054716565.79
Tail fiber proteinSAMEA3673003_00326Not AvailablePositive305497 - 30810395072.9
uncharacterised proteinSAMEA3673003_00327Not AvailablePositive308103 - 30896029285.6
Hypothetical proteinSAMEA3673003_00328Not AvailablePositive309069 - 3093059498.49
Hypothetical proteinSAMEA3673003_00329Not AvailablePositive309305 - 30962211161.3
AttrNot AvailableNot AvailablePositive309778 - 309805Not Available
Structural proteinSAMEA3673003_03939Not AvailableNegative4147643 - 415011791666.6

Displaying genes 61 – 70 of 5552 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total