Klebsiella pneumoniae strain EuSCAPE_PT021

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT021 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. It exhibits mobility through the presence of flagella and typically arranges itself in chains, pairs, or as single cells. This strain is mesophilic, with an optimal growth temperature of 37°C. Klebsiella pneumoniae is known for its pathogenicity, particularly in humans, where it can cause a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and meningitis. It is also implicated in intra-abdominal infections and can lead to complications such as liver abscesses and sepsis. Its ability to infect various hosts extends beyond humans, affecting a wide array of species including birds, mammals, and some plants. The strain is classified as nonsporulating and possesses a single replicon and double membrane structure, which is characteristic of Gram-negative bacteria. Its biotic relationship is noted as free-living, yet its significant pathogenic potential highlights its role in both human and animal health. This bacterium's diverse host range and the serious infections it can cause emphasize the importance of monitoring Klebsiella pneumoniae in clinical settings. Understanding its traits and pathogenic mechanisms is crucial for developing effective prevention and treatment strategies, especially in the face of rising antibiotic resistance among such pathogenic strains.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT021

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT021
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT021 genome assembly,

Gene Summary

Adenine Count

1179205 bp

Thymine Count

1174938 bp

Guanine Count

1566176 bp

Cytosine Count

1579647 bp

Genome Length

5499966 bp

Protein-coding Genes

4972 genes

Non-Coding Genes

184 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3649839_03654Not AvailablePositive3962699 - 396377840791.9
chromosome segregation protein smcSAMEA3649839_03655Not AvailablePositive3963768 - 396542663668.9
Portal proteinSAMEA3649839_03656Not AvailableNegative3965467 - 396649839073.9
OxidoreductaseSAMEA3649839_03657Not AvailableNegative3966498 - 396826466998.4
Gpo family capsid scaffolding proteinSAMEA3649839_03658Not AvailablePositive3968407 - 396924030574.8
Major capsid protein, p2 familySAMEA3649839_03659Not AvailablePositive3969257 - 397031539152.4
Terminase endonuclease subunitSAMEA3649839_03660Not AvailablePositive3970319 - 397096923777.6
Head completion/stabilization proteinSAMEA3649839_03661Not AvailablePositive3971065 - 397152917656.7
Tail protein xSAMEA3649839_03662Not AvailablePositive3971529 - 39717297464.88
HolinSAMEA3649839_03663Not AvailablePositive3971733 - 39719488113.98

Displaying genes 61 – 70 of 5156 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total