Klebsiella pneumoniae strain EuSCAPE_PT009

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT009 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It is classified as a chemoheterotroph and primarily thrives in host-associated environments, demonstrating a facultative anaerobic metabolism. The organism is mesophilic, with an optimal growth temperature of 37°C. This strain is notable for its diverse biotic relationships, being free-living yet capable of infecting a broad range of hosts, including Homo sapiens, Gallus gallus, various Metazoa, and several other animal species. Klebsiella pneumoniae is associated with multiple health effects, particularly in humans, where it can lead to severe conditions such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The pathogenicity of this strain is significant, contributing to complications like sepsis, neonatal sepsis, and pyogenic liver abscesses. With a single replicon and a double-membrane structure, Klebsiella pneumoniae strain EuSCAPE_PT009 exemplifies the complexity of microbial life and its adaptability to different environments. Its ability to cause infections across multiple species highlights its ecological versatility and potential impact on public health. Understanding the traits and behaviors of this strain is crucial for developing effective treatment and prevention strategies against the infections it can cause.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT009

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT009
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT009


Gene Summary

Adenine Count

1177144 bp

Thymine Count

1177448 bp

Guanine Count

1577902 bp

Cytosine Count

1568480 bp

Genome Length

5500974 bp

Protein-coding Genes

4972 genes

Non-Coding Genes

184 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
[nife] hydrogenase metallocenter assembly protein hypcSAMEA3649828_03708Not AvailableNegative4033451 - 40337239697.72
[nife] hydrogenase nickel incorporation-associated protein hypbSAMEA3649828_03709Not AvailableNegative4033714 - 403458631541.8
[nife] hydrogenase nickel incorporation protein hypaSAMEA3649828_03710Not AvailableNegative4034590 - 403493412954.5
formate hydrogenlyase regulatory protein hycaSAMEA3649828_03711Not AvailablePositive4035144 - 403559317116.2
formate hydrogenlyase subunit 2SAMEA3649828_03712Not AvailablePositive4035676 - 403628421849.3
formate hydrogenlyase subunit 3SAMEA3649828_03713Not AvailablePositive4036281 - 403810764002.1
formate hydrogenlyase subunit 4SAMEA3649828_03714Not AvailablePositive4038110 - 403903332905.3
formate hydrogenlyase subunit 5SAMEA3649828_03715Not AvailablePositive4039050 - 404075964982.1
formate hydrogenlyase complex 3 iron-sulfur proteinSAMEA3649828_03716Not AvailablePositive4040769 - 404131120579.8
formate hydrogenlyase subunit 7SAMEA3649828_03717Not AvailablePositive4041311 - 404207828166.2

Displaying genes 3781 – 3790 of 5156 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total