Klebsiella pneumoniae strain EuSCAPE_PT013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT013 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophy as its energy source. This strain is characterized by its ability to form chains, pairs, and singles in its cellular arrangement. It is motile, possessing flagella, and thrives optimally at a temperature of 37°C, falling within the mesophilic temperature range. EuSCAPE_PT013 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and other metazoan species, indicating a broad ecological niche. This strain has been implicated in numerous health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity primarily affects humans, but it can also impact various animals, suggesting a potential for interspecies transmission and environmental persistence. The presence of two membranes and a single replicon further defines its cellular structure. Notably, Klebsiella pneumoniae is nonsporulating, which may influence its survival strategies in different environments. Given its free-living biotic relationship, this strain is well-adapted to both host-associated and environmental contexts. The diversity of health effects attributed to Klebsiella pneumoniae strain EuSCAPE_PT013 underscores its significance in clinical microbiology, particularly in relation to infections that can arise in both humans and animals. The strain's capacity to cause severe infections highlights the importance of understanding its ecological dynamics and pathogenic mechanisms to address public health concerns effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT013 genome assembly,

Gene Summary

Adenine Count

1206122 bp

Thymine Count

1211319 bp

Guanine Count

1635369 bp

Cytosine Count

1591889 bp

Genome Length

5644699 bp

Protein-coding Genes

5131 genes

Non-Coding Genes

242 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rpir family transcriptional regulatorSAMEA3649832_02928Not AvailableNegative3094550 - 309529326338.8
pts system proteinSAMEA3649832_02929Not AvailablePositive3095554 - 309586210859.6
6-phospho-beta-glucosidaseSAMEA3649832_02930Not AvailablePositive3095953 - 309726047627.1
putative phosphotransferase proteinSAMEA3649832_02931Not AvailablePositive3097287 - 309863948625.0
alpha,alpha-phosphotrehalaseSAMEA3649832_02932Not AvailableNegative3098695 - 310035063403.3
pts system proteinSAMEA3649832_02933Not AvailableNegative3100402 - 310182050912.7
trehalose repressorSAMEA3649832_02934Not AvailableNegative3101951 - 310289834426.6
magnesium-transporting atpase mgtaSAMEA3649832_02935Not AvailablePositive3103278 - 310598699914.8
endoribonuclease l-pspSAMEA3649832_02936Not AvailableNegative3106059 - 310644513590.2
aspartate carbamoyltransferaseSAMEA3649832_02937Not AvailableNegative3106598 - 310705917132.6

Displaying genes 3071 – 3080 of 5373 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total