Klebsiella pneumoniae strain EuSCAPE_PT013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT013 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophy as its energy source. This strain is characterized by its ability to form chains, pairs, and singles in its cellular arrangement. It is motile, possessing flagella, and thrives optimally at a temperature of 37°C, falling within the mesophilic temperature range. EuSCAPE_PT013 is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and other metazoan species, indicating a broad ecological niche. This strain has been implicated in numerous health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity primarily affects humans, but it can also impact various animals, suggesting a potential for interspecies transmission and environmental persistence. The presence of two membranes and a single replicon further defines its cellular structure. Notably, Klebsiella pneumoniae is nonsporulating, which may influence its survival strategies in different environments. Given its free-living biotic relationship, this strain is well-adapted to both host-associated and environmental contexts. The diversity of health effects attributed to Klebsiella pneumoniae strain EuSCAPE_PT013 underscores its significance in clinical microbiology, particularly in relation to infections that can arise in both humans and animals. The strain's capacity to cause severe infections highlights the importance of understanding its ecological dynamics and pathogenic mechanisms to address public health concerns effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT013 genome assembly,

Gene Summary

Adenine Count

1206122 bp

Thymine Count

1211319 bp

Guanine Count

1635369 bp

Cytosine Count

1591889 bp

Genome Length

5644699 bp

Protein-coding Genes

5131 genes

Non-Coding Genes

242 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uronate isomeraseSAMEA3649832_01424Not AvailablePositive1487257 - 148866953785.9
altronate hydrolaseSAMEA3649832_01425Not AvailablePositive1488688 - 149017554069.3
inner membrane protein ygjvSAMEA3649832_01426Not AvailablePositive1490305 - 149085920400.6
sodium:dicarboxylate symporterSAMEA3649832_01427Not AvailableNegative1490875 - 149212243482.4
integral membrane protein tercSAMEA3649832_01428Not AvailableNegative1492389 - 149336036022.3
oxidoreductaseSAMEA3649832_01429Not AvailableNegative1493632 - 149462136217.1
metal-dependent hydrolaseSAMEA3649832_01430Not AvailableNegative1494695 - 149519519142.3
xre family transcriptional regulatorSAMEA3649832_01431Not AvailableNegative1495215 - 149581721206.6
b3/4 domain-containing proteinSAMEA3649832_01432Not AvailablePositive1495861 - 149656825560.5
23s rrna (guanine-n-2-) -methyltransferase rlmgSAMEA3649832_01433Not AvailablePositive1496654 - 149778441903.0

Displaying genes 1611 – 1620 of 5373 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total