Klebsiella pneumoniae strain EuSCAPE_PT002

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT002 is a facultative anaerobic, Gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain is classified as a chemoheterotroph, deriving energy from organic compounds. It typically exists in various arrangements, including chains, pairs, and singles. The optimal growth temperature for EuSCAPE_PT002 is 37°C, placing it within the mesophilic temperature range. This strain is notable for its diverse biotic relationships, being free-living and associated with numerous hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. Such a wide host range highlights its potential ecological versatility and ability to adapt to different environments. Klebsiella pneumoniae is well-documented for its pathogenicity in humans, causing a range of serious health issues such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain is implicated in conditions like neonatal sepsis and septicemia, underscoring its clinical significance and impact on public health. The observation that EuSCAPE_PT002 is nonsporulating further emphasizes its lifestyle and adaptability in host-associated environments. In summary, Klebsiella pneumoniae strain EuSCAPE_PT002 exemplifies a significant pathogen with a complex interaction with its hosts, contributing to various health complications and highlighting the importance of monitoring its prevalence and resistance patterns in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT002

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT002
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT002 genome assembly,

Gene Summary

Adenine Count

1177532 bp

Thymine Count

1177131 bp

Guanine Count

1571418 bp

Cytosine Count

1575185 bp

Genome Length

5501266 bp

Protein-coding Genes

4971 genes

Non-Coding Genes

184 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutathione s-transferase, thetaSAMEA3649821_00318Not AvailableNegative329946 - 33056323107.0
amino acid abc transporter periplasmic amino acid-binding proteinSAMEA3649821_00319Not AvailableNegative330641 - 33151931051.1
amino acid abc transporterSAMEA3649821_00320Not AvailableNegative331531 - 33231028928.8
amino acid abc transporter permeaseSAMEA3649821_00321Not AvailableNegative332294 - 33322033943.9
n-acetyltransferase gcn5SAMEA3649821_00322Not AvailableNegative333230 - 33373919405.9
periplasmic binding proteinSAMEA3649821_00323Not AvailableNegative333751 - 33468332631.0
nitrilotriacetate monooxygenase component aSAMEA3649821_00324Not AvailableNegative334701 - 33601448732.0
n-acetyl-l,l-diaminopimelate deacetylaseSAMEA3649821_00325Not AvailableNegative336039 - 33716040452.9
luciferase family protein ytmoSAMEA3649821_00326Not AvailableNegative337150 - 33815736367.2
dna topology modulation proteinSAMEA3649821_00327Not AvailableNegative338249 - 33880021645.8

Displaying genes 431 – 440 of 5155 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total