Klebsiella pneumoniae strain EuSCAPE_DK013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_DK013 is a gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle and is classified as a chemoheterotroph. It demonstrates mobility due to the presence of flagella and can exist in various cell arrangements, including chains, pairs, and singles. The strain is mesophilic, with an optimal growth temperature of 37°C. This bacterium is known to be free-living and associated with a diverse range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa, Viridiplantae, and domestic animals such as Canis lupus familiaris and Sus scrofa. The broad host range indicates its versatility in colonizing different biological environments. Klebsiella pneumoniae strain EuSCAPE_DK013 is associated with numerous health complications in humans, including bacteremia, urinary tract infections, pneumonia, and a variety of intra-abdominal infections. The strain's pathogenicity is particularly concerning in hospital settings, where it can lead to severe outcomes such as sepsis and neonatal sepsis. The ability of this strain to thrive in multiple host environments highlights its ecological adaptability and potential for transmission across species. Understanding its pathogenic mechanisms and ecological interactions is crucial for developing effective strategies to mitigate the health risks posed by Klebsiella pneumoniae, particularly in clinical settings where it may cause significant morbidity and mortality.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_DK013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_DK013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_DK013 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4726 genes

Non-Coding Genes

645 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3649809_04329Not AvailablePositive4652109 - 465248913954.5
lipoproteinSAMEA3649809_04330Not AvailablePositive4652500 - 465279910969.1
Hypothetical proteinSAMEA3649809_04331Not AvailablePositive4652955 - 465338616691.1
Hypothetical proteinSAMEA3649809_04332Not AvailablePositive4653506 - 465451336359.7
Dna polymerase iSAMEA3649809_04333Not AvailablePositive4654574 - 465551835662.1
Hypothetical proteinSAMEA3649809_04334Not AvailablePositive4655518 - 46557849589.76
Putative reca-like recombinaseSAMEA3649809_04335Not AvailablePositive4655787 - 465686338935.4
Hypothetical proteinSAMEA3649809_04336Not AvailablePositive4657573 - 465790812327.7
Putative cre-associated proteinSAMEA3649809_04337Not AvailablePositive4657908 - 46581208381.21
Putative replication protein repaSAMEA3649809_04338Not AvailableNegative4658573 - 465967041580.2

Displaying genes 141 – 150 of 5371 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total