Klebsiella pneumoniae strain EuSCAPE_GR166

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR166 is a Gram-negative, rod-shaped bacterium that displays a varied cell arrangement consisting of chains, pairs, and singles. It is a facultative anaerobe, indicating its ability to thrive in both the presence and absence of oxygen, and it is categorized as a chemoheterotroph, utilizing organic compounds as its energy source. This strain possesses flagella, contributing to its mobility, and is classified as mesophilic, with an optimal growth temperature of 37°C. Ecologically, K. pneumoniae strain EuSCAPE_GR166 is primarily host-associated, having a wide range of potential hosts including Homo sapiens, Gallus gallus, and various other metazoans and plants. Its free-living nature suggests it can also survive outside of host organisms, indicating a versatile ecological adaptability. Clinically, K. pneumoniae strain EuSCAPE_GR166 is associated with various severe health effects, including bacteremia, urinary tract infections, pneumonia, and several types of abscesses. Its pathogenicity is particularly noted in human hosts, where it can lead to conditions such as sepsis and neonatal sepsis. The strain's ability to cause a diverse array of infections highlights its significant role in human health and disease. Understanding its characteristics and interactions with different hosts can provide insights into its ecological role and potential impacts on public health, particularly concerning antibiotic resistance and emerging infectious diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR166

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR166
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR166 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

5070 genes

Non-Coding Genes

400 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative hnh endonucleaseSAMEA3649784_02169Not AvailablePositive2251259 - 225178919962.4
Bacteriophage antiterminator protein qSAMEA3649784_02170Not AvailablePositive2251786 - 225247525947.9
Lysr family transcriptional regulatorSAMEA3649784_02336Not AvailablePositive2421907 - 242279133132.1
Nucleotidyltransferase domain-containing proteinSAMEA3649784_02337Not AvailablePositive2422916 - 242371630046.4
AttlNot AvailableNot AvailablePositive2423991 - 2424037Not Available
Hypothetical proteinSAMEA3649784_02338Not AvailableNegative2424151 - 242570160292.0
Site-specific integraseSAMEA3649784_02339Not AvailableNegative2425698 - 242672338585.7
Repressor proteinSAMEA3649784_02340Not AvailableNegative2426726 - 242713014825.8
Rha family transcriptional regulatorSAMEA3649784_02341Not AvailablePositive2427514 - 24277207893.57
Regulatory protein ciiSAMEA3649784_02342Not AvailablePositive2427753 - 242826218263.1

Displaying genes 131 – 140 of 5482 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total