Klebsiella pneumoniae strain EuSCAPE_GR158

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR158 is a Gram-negative, rod-shaped bacterium characterized as a chemoheterotroph and a facultative anaerobe. It is capable of mobility, equipped with flagella, and typically forms chains, pairs, or exists as singles. This strain thrives at an optimal temperature of 37°C, placing it within the mesophilic range. The ecological niche of Klebsiella pneumoniae EuSCAPE_GR158 is primarily host-associated, with a diverse array of hosts including Homo sapiens, various species within Metazoa, and domesticated animals such as Gallus gallus and Sus scrofa. This wide host range suggests a significant ecological flexibility and adaptability, allowing it to inhabit multiple environments and interact with different biological systems. Health-wise, Klebsiella pneumoniae strain EuSCAPE_GR158 is known to be pathogenic to humans, associated with a variety of serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. The strain's ability to cause a range of infections, including neonatal sepsis and intra-abdominal infections, highlights its clinical relevance and potential threat to human health. The bacterium does not form spores, which may influence its survival strategies in host-associated environments. Understanding the pathogenic potential and ecological interactions of Klebsiella pneumoniae strain EuSCAPE_GR158 is crucial for developing effective therapeutic interventions and managing infections caused by this organism. Its presence in diverse hosts indicates that monitoring and controlling its spread is essential for public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR158

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR158
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR158 genome assembly,

Gene Summary

Adenine Count

1220793 bp

Thymine Count

1226180 bp

Guanine Count

1629357 bp

Cytosine Count

1612022 bp

Genome Length

5688352 bp

Protein-coding Genes

5103 genes

Non-Coding Genes

412 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
oxaloacetate decarboxylase gamma chainSAMEA3649777_01563Not AvailableNegative1628968 - 16292198909.29
na(+)citrate oh(-) antiporterSAMEA3649777_01564Not AvailableNegative1629366 - 163070647504.7
[citrate (pro-3s)-lyase] ligaseSAMEA3649777_01565Not AvailablePositive1630963 - 163199138469.8
citrate lyase subunit gammaSAMEA3649777_01566Not AvailablePositive1632022 - 163231510427.7
citrate lyase subunit betaSAMEA3649777_01567Not AvailablePositive1632312 - 163318131353.7
citrate lyase subunit alphaSAMEA3649777_01568Not AvailablePositive1633192 - 163471854682.5
triphosphoribosyl-dephospho-coa synthaseSAMEA3649777_01569Not AvailablePositive1634737 - 163564532656.5
dihydrodipicolinate reductaseSAMEA3649777_01570Not AvailablePositive1635874 - 163669528649.4
carbamoyl phosphate synthase small subunitSAMEA3649777_01571Not AvailablePositive1637153 - 163830141174.0
carbamoyl-phosphate synthase large subunitSAMEA3649777_01572Not AvailablePositive1638319 - 1641543118005.0

Displaying genes 1851 – 1860 of 5515 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total