Klebsiella pneumoniae strain EuSCAPE_GR162

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR162 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of existing in various forms, including chains, pairs, and singles, and possesses flagella, allowing for mobility. It is classified as mesophilic, with an optimal growth temperature of 37°C. The habitat of K. pneumoniae strain EuSCAPE_GR162 is primarily host-associated, indicating its adaptation to living in association with various hosts. It has been identified in a wide range of organisms, including Homo sapiens (humans), Gallus gallus (domestic chickens), and other metazoans and vertebrates such as Danio rerio (zebrafish) and Sus scrofa (pigs). This diverse host range reflects its ecological versatility and potential for transmission among species. K. pneumoniae strain EuSCAPE_GR162 is known for its pathogenicity in humans, causing a variety of health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its nonsporulating nature suggests that it relies on direct transmission and environmental adaptability rather than sporulation for survival and propagation. This strain’s free-living biotic relationship, combined with its pathogenic potential in multiple hosts, underscores its significance in both clinical microbiology and ecology. Understanding the interactions between K. pneumoniae and its hosts can help inform strategies for infection control and management, highlighting the importance of monitoring its prevalence across different environments and species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR162

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR162
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR162 genome assembly,

Gene Summary

Adenine Count

1141610 bp

Thymine Count

1146083 bp

Guanine Count

1541430 bp

Cytosine Count

1522871 bp

Genome Length

5351994 bp

Protein-coding Genes

4876 genes

Non-Coding Genes

173 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cell volume regulation protein aSAMEA3649780_01873Not AvailableNegative1957845 - 195957862160.2
muramoyltetrapeptide carboxypeptidaseSAMEA3649780_01874Not AvailableNegative1959671 - 196058533361.1
membrane-bound lytic murein transglycosylase eSAMEA3649780_01875Not AvailablePositive1960761 - 196137222359.1
ferrioxamine receptorSAMEA3649780_01876Not AvailableNegative1961414 - 196353477402.5
trehalaseSAMEA3649780_01877Not AvailableNegative1963788 - 196553364275.6
domain of uncharacterised function (duf404)SAMEA3649780_01878Not AvailablePositive1965918 - 196735754497.3
bacterial domain of uncharacterised function (duf403)SAMEA3649780_01879Not AvailablePositive1967351 - 196828035289.3
protein containing transglutaminase-like domainSAMEA3649780_01880Not AvailablePositive1968277 - 196909230371.9
putative proteasome-type proteaseSAMEA3649780_01881Not AvailablePositive1969109 - 196985527604.8
putative fatty acid desaturaseSAMEA3649780_01882Not AvailablePositive1970267 - 197128039206.4

Displaying genes 1991 – 2000 of 5049 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total