Klebsiella pneumoniae strain EuSCAPE_GR149

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR149 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and utilizes chemoheterotrophic energy sources. This strain is capable of existing in various cell arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. It thrives optimally at a temperature of 37°C, classifying it as mesophilic, and possesses a single replicon and a double membrane structure. As a host-associated organism, Klebsiella pneumoniae strain EuSCAPE_GR149 has a broad range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans, plants, and mammals. Its biotic relationship is categorized as free-living. This strain is notable for its pathogenicity in humans, being associated with numerous health complications such as bacteremia, urinary tract infections, pneumonia, and various types of abscesses. It is also linked to severe conditions like meningitis, sepsis, and neonatal infections. The bacterium’s capacity to cause such a diverse array of infections underscores its clinical significance. From a biological perspective, the ability of Klebsiella pneumoniae strain EuSCAPE_GR149 to inhabit a wide range of hosts and cause serious infections in humans highlights its adaptability and potential role in public health. Its presence in different environments and associations with various species suggest that it may act as a reservoir of pathogenic traits, contributing to the dynamics of microbial ecology and the spread of antibiotic resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR149

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR149
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR149 genome assembly,

Gene Summary

Adenine Count

1196026 bp

Thymine Count

1200791 bp

Guanine Count

1616542 bp

Cytosine Count

1584070 bp

Genome Length

5597429 bp

Protein-coding Genes

5024 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3649768_01161Not AvailablePositive1192994 - 119342515919.8
Virion morphogenesis proteinSAMEA3649768_01162Not AvailablePositive1193418 - 119386417426.2
Hypothetical proteinSAMEA3649768_01163Not AvailableNegative1193861 - 119455326276.5
Baseplate assembly protein vSAMEA3649768_01164Not AvailablePositive1194648 - 119522020657.2
Baseplate assembly proteinSAMEA3649768_01165Not AvailablePositive1195217 - 119557913243.9
Baseplate assembly protein jSAMEA3649768_01166Not AvailablePositive1195566 - 119647432702.6
Tail protein iSAMEA3649768_01167Not AvailablePositive1196467 - 119706622453.5
Spore coat proteinSAMEA3649768_01168Not AvailablePositive1197068 - 1200019108679.0
Concanavalin a-like lectin/glucanase superfamily proteinSAMEA3649768_01169Not AvailablePositive1200023 - 120075425659.7
Hypothetical proteinSAMEA3649768_01170Not AvailablePositive1200751 - 12009547584.69

Displaying genes 61 – 70 of 5382 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total