Klebsiella pneumoniae strain EuSCAPE_GR147

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR147 is a Gram-negative, rod-shaped bacterium that exhibits a variety of pathogenic traits, primarily in humans (Homo sapiens) but also in a range of other hosts, including Gallus gallus, various Metazoa, and several other animals. This strain is classified as a chemoheterotroph and can thrive as a facultative anaerobe, allowing it to adapt to varying oxygen levels in its environment. The bacterium is capable of movement, possessing flagella, and typically arranges itself in chains, pairs, or singles. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, ideal for survival in warm-blooded hosts. Notably, EuSCAPE_GR147 has a simple genomic structure with a single replicon and two membranes, characteristic of many Gram-negative bacteria. Klebsiella pneumoniae is associated with numerous severe health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It is also implicated in more serious conditions such as sepsis and neonatal sepsis. The strain's pathogenicity is significant, demonstrating its potential to cause disease in humans. The ecological insight from this data indicates that Klebsiella pneumoniae strain EuSCAPE_GR147 occupies a diverse array of ecological niches as a free-living organism, suggesting its ability to adapt and persist in various environments. This adaptability, coupled with its pathogenic potential, underscores the importance of monitoring and managing infections caused by this strain in both human and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR147

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR147
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR147 genome assembly,

Gene Summary

Adenine Count

1242457 bp

Thymine Count

1233256 bp

Guanine Count

1629250 bp

Cytosine Count

1647434 bp

Genome Length

5752397 bp

Protein-coding Genes

5164 genes

Non-Coding Genes

287 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type 1 fimbrial proteinSAMEA3649766_03787Not AvailablePositive4024079 - 402464218895.3
putative fimbrial biogenesis periplasmic chaperoneSAMEA3649766_03788Not AvailablePositive4024701 - 402538725433.6
putative fimbrial biogenesis outer membrane usher proteinSAMEA3649766_03789Not AvailablePositive4025423 - 402796692347.1
fimbrial proteinSAMEA3649766_03790Not AvailablePositive4027990 - 402900636611.7
membrane proteinSAMEA3649766_03791Not AvailablePositive4029341 - 402969111753.2
colicin v secretion protein cvaaSAMEA3649766_03792Not AvailablePositive4029795 - 403108148325.8
putative secretion atpaseSAMEA3649766_03793Not AvailablePositive4031188 - 403319774900.8
uncharacterised proteinSAMEA3649766_03794Not AvailablePositive4033212 - 403407532510.5
membrane protein yjeiSAMEA3649766_03795Not AvailableNegative4034130 - 403448312014.2
heat shock protein 60 family chaperone groelSAMEA3649766_03796Not AvailableNegative4034744 - 403639057129.0

Displaying genes 3921 – 3930 of 5451 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total