Klebsiella pneumoniae strain EuSCAPE_GR134

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR134 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and is classified as a chemoheterotroph. This strain typically exists in chains, pairs, or as single cells, and possesses flagella, indicating mobility. It has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. This strain is primarily host-associated, with a diverse array of potential hosts including Homo sapiens, various species of birds (Phasianidae, Aves), mammals (Canis lupus familiaris, Sus scrofa, Equidae), and aquatic organisms such as Danio rerio. Its ability to thrive in different environments underscores its ecological versatility and adaptability. Klebsiella pneumoniae strain EuSCAPE_GR134 is known for its pathogenicity in humans, where it is associated with a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis. It can lead to various complications such as liver abscesses, meningitis, and wound infections. The bacterium's capability to cause such diverse infections highlights its potential as a significant opportunistic pathogen. In summary, Klebsiella pneumoniae strain EuSCAPE_GR134 exemplifies a free-living, pathogenic organism with a wide host range and significant clinical relevance. Its adaptability to various environments and ability to cause severe infections in humans and other species serve as a reminder of the intricate relationships between microorganisms and their hosts in ecological and health contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR134

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR134
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR134 genome assembly,

Gene Summary

Adenine Count

1206963 bp

Thymine Count

1206833 bp

Guanine Count

1596915 bp

Cytosine Count

1622184 bp

Genome Length

5632895 bp

Protein-coding Genes

5151 genes

Non-Coding Genes

235 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sensor kinase cussSAMEA3649753_04993Not AvailablePositive5226737 - 522821255805.4
sileSAMEA3649753_04994Not AvailablePositive5228463 - 522889415357.1
putative transposaseSAMEA3649753_04995Not AvailableNegative5229190 - 522959415241.0
insertion element proteinSAMEA3649753_04996Not AvailableNegative5229748 - 523004111468.0
is2 repressor tnpaSAMEA3649753_04997Not AvailablePositive5230296 - 523069114634.9
putative transposaseSAMEA3649753_04998Not AvailablePositive5230649 - 523153033584.7
putative transposaseSAMEA3649753_04999Not AvailablePositive5232125 - 523241811493.1
secondary glycine betaine transporter betuSAMEA3649753_05000Not AvailablePositive5232570 - 523456773732.5
uncharacterised proteinSAMEA3649753_05001Not AvailablePositive5234512 - 52346193957.75
predicted membrane protein (duf2254)SAMEA3649753_05002Not AvailablePositive5234630 - 523590746806.4

Displaying genes 5001 – 5010 of 5386 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total