Klebsiella pneumoniae strain EuSCAPE_PT100

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT100 is a Gram-negative, rod-shaped bacterium that thrives as a facultative anaerobe, utilizing a chemoheterotrophic energy source. This strain is characterized by its ability to exist in various cellular arrangements including chains, pairs, and singles. It possesses flagella, which enable mobility, and it has a mesophilic optimal growth temperature of 37°C. EuSCAPE_PT100 is primarily host-associated, indicating its ecological niche is closely linked to various hosts, including Homo sapiens, Gallus gallus, and multiple other Metazoa and Viridiplantae. This broad host range suggests a significant ecological adaptability and potential for transmission across different species. The strain is notable for its pathogenicity in humans, contributing to a wide range of health complications such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The extensive list of health effects associated with Klebsiella pneumoniae emphasizes its role as a major opportunistic pathogen, particularly in immunocompromised individuals or those with underlying health issues. As a nonsporulating organism with a single replicon and a double membrane structure, Klebsiella pneumoniae strain EuSCAPE_PT100 exemplifies the complexity of microbial life in host-associated environments. Its pathogenic capabilities and versatility in host range indicate an important ecological role within both human health and the broader ecosystem, particularly in the context of emerging antibiotic resistance challenges.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT100

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT100
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT100 genome assembly,

Gene Summary

Adenine Count

1204764 bp

Thymine Count

1203078 bp

Guanine Count

1592978 bp

Cytosine Count

1605602 bp

Genome Length

5606422 bp

Protein-coding Genes

5116 genes

Non-Coding Genes

199 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cfa/i fimbrial chaperoneSAMEA3649913_00558Not AvailableNegative560978 - 56168826579.9
cfa/i fimbrial minor adhesinSAMEA3649913_00559Not AvailableNegative561657 - 56330059670.7
cfa/i fimbrial subunit c usher proteinSAMEA3649913_00560Not AvailableNegative563290 - 56581590768.1
cfa/i fimbrial auxiliary subunitSAMEA3649913_00561Not AvailableNegative565841 - 56650924309.2
fimbrillin matbSAMEA3649913_00562Not AvailableNegative566568 - 56715520077.5
regulator of cfa/i fimbriaeSAMEA3649913_00563Not AvailableNegative567231 - 56777321179.7
phosphonate transport atp-binding proteinSAMEA3649913_00564Not AvailablePositive568622 - 56946430645.2
phosphonate abc transporter substrate-binding proteinSAMEA3649913_00565Not AvailablePositive569487 - 57042533604.3
putative inner membrane permease of abc transporterSAMEA3649913_00566Not AvailablePositive570492 - 57136432274.0
phosphonate abc transporter permeaseSAMEA3649913_00567Not AvailablePositive571361 - 57224532806.8

Displaying genes 621 – 630 of 5315 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total