Klebsiella pneumoniae strain EuSCAPE_PT094

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT094 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. It is characterized by its ability to form chains, pairs, and singles, and possesses flagella, indicating mobility. The bacterium thrives optimally at 37°C, falling within the mesophilic temperature range, and is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and various metazoan and plant species. This strain is notable for its pathogenicity in humans, being linked to a wide range of health complications such as bacteremia, urinary tract infections, pneumonia, and meningitis, among others. Its capacity to cause severe infections, including neonatal sepsis and pyogenic liver abscesses, highlights its significance as a public health concern. Klebsiella pneumoniae EuSCAPE_PT094 is nonsporulating and possesses a single replicon along with two membranes, a common feature of Gram-negative bacteria. Its biotic relationship is described as free-living, suggesting a versatile ecological role beyond human hosts. Given its diverse range of hosts and the serious health effects associated with infections, understanding the ecological dynamics of Klebsiella pneumoniae strain EuSCAPE_PT094 is critical. The bacterium's adaptability to various environments and hosts may contribute to its persistence and transmission, emphasizing the need for continued surveillance and research to mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT094

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT094
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT094 genome assembly,

Gene Summary

Adenine Count

1234042 bp

Thymine Count

1229434 bp

Guanine Count

1636123 bp

Cytosine Count

1649430 bp

Genome Length

5749029 bp

Protein-coding Genes

5071 genes

Non-Coding Genes

378 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sulfate adenylyltransferaseSAMEA3649908_01732Not AvailablePositive1910406 - 191183352494.4
adenylylsulfate kinaseSAMEA3649908_01733Not AvailablePositive1911833 - 191243822505.7
cytochrome oxidase subunitSAMEA3649908_01734Not AvailablePositive1912489 - 191281511788.8
cell division protein ftsbSAMEA3649908_01735Not AvailablePositive1912956 - 191327311952.1
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferaseSAMEA3649908_01736Not AvailablePositive1913293 - 191400325625.8
2-c-methyl-d-erythritol 2,4-cyclo diphosphate synthaseSAMEA3649908_01737Not AvailablePositive1914003 - 191448216955.6
trna pseudouridine 13 synthaseSAMEA3649908_01738Not AvailablePositive1914479 - 191552839104.6
stationary phase survival protein sureSAMEA3649908_01739Not AvailablePositive1915509 - 191627027366.5
protein-l-isoaspartate o-methyltransferaseSAMEA3649908_01740Not AvailablePositive1916264 - 191689023407.3
lipoprotein nlpdSAMEA3649908_01741Not AvailablePositive1917016 - 191815239331.1

Displaying genes 2021 – 2030 of 5449 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total