Klebsiella pneumoniae strain EuSCAPE_GR101

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR101 is a Gram-negative bacterium that exhibits a rod shape and is characterized by its ability to form chains, pairs, and singles. This strain is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is motile, with flagella present, and is classified as a chemoheterotroph, relying on organic compounds for energy. The optimal growth temperature for EuSCAPE_GR101 is 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and has a double membrane structure, typical of many Gram-negative bacteria. This strain is free-living but is also associated with a variety of hosts, including humans (Homo sapiens), birds (Gallus gallus), and various other metazoan species, indicating a broad ecological niche. Klebsiella pneumoniae strain EuSCAPE_GR101 has significant health implications, being associated with a range of serious infections in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The strain's pathogenicity is particularly noted in its ability to cause sepsis and other severe conditions, such as pyogenic liver abscesses and early onset neonatal sepsis. Ecologically, the wide host range of Klebsiella pneumoniae strain EuSCAPE_GR101 suggests that it may play a versatile role in various environments, potentially influencing both human health and animal health across different species. Its presence in diverse biological contexts underscores the importance of monitoring this pathogen, considering its implications for public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR101

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR101
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR101 genome assembly,

Gene Summary

Adenine Count

1177547 bp

Thymine Count

1176355 bp

Guanine Count

1583385 bp

Cytosine Count

1569724 bp

Genome Length

5507011 bp

Protein-coding Genes

5025 genes

Non-Coding Genes

167 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
periplasmic binding proteinSAMEA3649720_03344Not AvailableNegative3576971 - 357790332631.0
nitrilotriacetate monooxygenase component aSAMEA3649720_03345Not AvailableNegative3577921 - 357923448732.0
n-acetyl-l,l-diaminopimelate deacetylaseSAMEA3649720_03346Not AvailableNegative3579259 - 358038040452.9
luciferase family protein ytmoSAMEA3649720_03347Not AvailableNegative3580370 - 358137736377.2
dna topology modulation proteinSAMEA3649720_03348Not AvailableNegative3581469 - 358202021605.8
lysr family transcriptional regulatorSAMEA3649720_03349Not AvailablePositive3582293 - 358318032861.7
l-asparagine permeaseSAMEA3649720_03350Not AvailablePositive3583370 - 358482452389.1
outer membrane lipoproteinSAMEA3649720_03351Not AvailableNegative3584875 - 35850967872.46
putative receptorSAMEA3649720_03352Not AvailableNegative3585265 - 358632638329.6
tonb-dependent receptor yncdSAMEA3649720_03353Not AvailablePositive3586585 - 358869077125.8

Displaying genes 3421 – 3430 of 5192 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total