Klebsiella pneumoniae strain EuSCAPE_PT049

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT049 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic respiration mode. This strain has a mobility feature, indicated by the presence of flagella, which allows it to move in various environments. It is a chemoheterotroph, indicating that it derives energy from organic compounds, and it thrives optimally at 37°C, placing it within the mesophilic temperature range. This bacterium is primarily host-associated, with documented relationships with a wide variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other metazoans and plants. Its biotic relationship is characterized as free-living, implying that it can survive independently in its environment. Klebsiella pneumoniae strain EuSCAPE_PT049 is notable for its pathogenicity in humans, being responsible for a range of serious health issues such as bacteremia, urinary tract infections, pneumonia, and various abdominal infections. It is linked to conditions like sepsis, neonatal sepsis, and pyogenic liver abscesses, among others. The broad spectrum of infections it can cause highlights its clinical significance and the potential for severe health impacts. The ability of this strain to inhabit multiple hosts, coupled with its pathogenicity, suggests a significant ecological role in disease transmission and persistence in various environments. Understanding the dynamics of Klebsiella pneumoniae strain EuSCAPE_PT049 could be critical for managing its impact on public health and for developing effective treatment strategies against the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT049

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT049
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT049 genome assembly,

Gene Summary

Adenine Count

1189341 bp

Thymine Count

1192201 bp

Guanine Count

1584524 bp

Cytosine Count

1582805 bp

Genome Length

5548871 bp

Protein-coding Genes

5016 genes

Non-Coding Genes

180 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
quinone oxidoreductaseSAMEA3649863_00031Not AvailablePositive34484 - 3546134462.5
nucleoside recognition family proteinSAMEA3649863_00032Not AvailablePositive35581 - 3651332979.7
membrane proteinSAMEA3649863_00033Not AvailableNegative36424 - 3804659919.7
histidine kinaseSAMEA3649863_00034Not AvailablePositive38319 - 385649236.05
amp nucleosidaseSAMEA3649863_00035Not AvailablePositive38694 - 4014854233.3
Trna-asnNot AvailableNot AvailablePositive40307 - 40382Not Available
mate family multidrug exporterSAMEA3649863_00037Not AvailableNegative40511 - 4194751997.9
Trna-asnNot AvailableNot AvailablePositive42140 - 42215Not Available
integraseSAMEA3649863_00039Not AvailablePositive42396 - 4367049078.4
spntSAMEA3649863_00040Not AvailableNegative43717 - 4510553319.0

Displaying genes 141 – 150 of 5196 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total