Klebsiella pneumoniae strain EuSCAPE_PT043

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT043 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and can be found in various arrangements, including chains, pairs, and singles. This strain is a chemoheterotroph, deriving its energy from organic compounds, and has a temperature range optimal for growth at 37°C, classifying it as mesophilic. The bacterium is motile, possessing flagella, which may contribute to its ability to colonize different environments. EuSCAPE_PT043 is primarily host-associated, with a diverse range of hosts including Homo sapiens, Gallus gallus, and various other metazoans and plants. This broad host range indicates its adaptability and potential for transmission across species. Klebsiella pneumoniae is known for its significant health impacts, being associated with various infections such as bacteremia, urinary tract infections, pneumonia, and meningitis, among others. This pathogenicity in humans highlights the strain’s role as a serious clinical threat, particularly in immunocompromised individuals. Given its free-living biotic relationship and nonsporulating nature, Klebsiella pneumoniae strain EuSCAPE_PT043 exemplifies the challenges faced in infection control, especially in hospital settings. The strain's ability to thrive in diverse environments, combined with its pathogenic capabilities, underscores the importance of monitoring and understanding its epidemiology to mitigate health risks associated with this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT043

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT043
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT043 genome assembly,

Gene Summary

Adenine Count

1207297 bp

Thymine Count

1210480 bp

Guanine Count

1635744 bp

Cytosine Count

1591870 bp

Genome Length

5645391 bp

Protein-coding Genes

5129 genes

Non-Coding Genes

242 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive2271108 - 2271120Not Available
Putative integraseSAMEA3649857_02163Not AvailablePositive2282908 - 228407444660.3
uncharacterised proteinSAMEA3649857_02164Not AvailablePositive2284133 - 228544650209.4
EndodeoxyribonucleaseSAMEA3649857_02165Not AvailableNegative2285695 - 228625220903.9
Hypothetical proteinSAMEA3649857_02166Not AvailableNegative2286254 - 228678419440.9
Hypothetical proteinSAMEA3649857_02167Not AvailableNegative2286795 - 228754728352.7
Transcriptional regulatorSAMEA3649857_02168Not AvailableNegative2287862 - 228872231365.2
Hypothetical proteinSAMEA3649857_02169Not AvailableNegative2288799 - 228961130511.1
Hypothetical proteinSAMEA3649857_02170Not AvailableNegative2289655 - 229001413036.7
uncharacterised proteinSAMEA3649857_02171Not AvailablePositive2290454 - 229136834672.1

Displaying genes 1 – 10 of 5371 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total