Klebsiella pneumoniae strain EuSCAPE_PT044

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PT044 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain demonstrates a versatile cell arrangement, occurring in chains, pairs, and singles, and exhibits mobility due to the presence of flagella. It thrives optimally at 37°C, fitting within the mesophilic temperature range. EuSCAPE_PT044 is primarily host-associated, with a wide array of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and vertebrates such as Danio rerio (zebrafish) and Canis lupus familiaris (domestic dogs). This extensive host range indicates its ecological adaptability and potential for cross-species transmission. The strain is nonsporulating and possesses a single replicon and a double membrane structure. It is known for its pathogenicity in humans, associated with numerous health conditions such as bacteremia, urinary tract infections, pneumonia, and more severe infections like sepsis and meningitis. The diverse health effects linked to EuSCAPE_PT044 underscore its clinical significance and the potential complications arising from infections. In summary, the ecological versatility and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_PT044 highlight the importance of monitoring this bacterium in both clinical and environmental contexts. Its ability to infect a wide range of hosts suggests that it plays a significant role in microbial communities and human health dynamics, emphasizing the need for continued research and surveillance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PT044

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PT044
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PT044 genome assembly,

Gene Summary

Adenine Count

1130653 bp

Thymine Count

1142898 bp

Guanine Count

1546876 bp

Cytosine Count

1525038 bp

Genome Length

5345465 bp

Protein-coding Genes

4852 genes

Non-Coding Genes

253 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane siderophore receptor ironSAMEA3649858_03203Not AvailableNegative3396710 - 339889380116.3
intracellular septation protein ispaSAMEA3649858_03204Not AvailableNegative3399165 - 339970420933.3
membrane protein ycic, linked to ispaSAMEA3649858_03205Not AvailableNegative3399759 - 340050226352.6
putative ferredoxinSAMEA3649858_03206Not AvailableNegative3400528 - 340094114796.4
outer membrane protein wSAMEA3649858_03207Not AvailablePositive3401211 - 340184922985.2
iron-uptake factor piucSAMEA3649858_03208Not AvailableNegative3401934 - 340261125359.2
ferrichrome-iron receptorSAMEA3649858_03209Not AvailableNegative3402660 - 340494581595.2
short-chain dehydrogenase/reductase sdrSAMEA3649858_03210Not AvailableNegative3405255 - 340596225714.1
uncharacterised proteinSAMEA3649858_03211Not AvailablePositive3406081 - 340635310072.2
quinone oxidoreductaseSAMEA3649858_03212Not AvailableNegative3406389 - 340733632525.1

Displaying genes 3361 – 3370 of 5105 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total