Klebsiella pneumoniae strain EuSCAPE_GR098

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR098 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, obtaining energy as a chemoheterotroph. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and is motile due to the presence of flagella. It has a mesophilic optimal growth temperature of 37°C, with the ability to thrive within a defined temperature range. EuSCAPE_GR098 is associated with multiple hosts, including Homo sapiens, various species of birds, mammals, and even plants. This broad host range highlights its ecological versatility and potential role in diverse biotic relationships, as it is classified as free-living. The health impact of K. pneumoniae strain EuSCAPE_GR098 is significant, as it is associated with a variety of severe infections in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity is well-documented, with the bacterium causing complications such as liver abscesses and meningitis, underscoring its role as a critical human pathogen. The strain has a single replicon and two membranes, characteristic of Gram-negative bacteria. Notably, it does not form spores, which is consistent with its lifestyle and pathogenicity. The data provided emphasizes the importance of K. pneumoniae strain EuSCAPE_GR098 in both clinical settings and ecological contexts, illustrating its adaptability and potential risks to human health. This understanding is crucial for developing strategies to manage infections caused by this pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR098

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR098
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR098 genome assembly,

Gene Summary

Adenine Count

1149595 bp

Thymine Count

1150027 bp

Guanine Count

1552653 bp

Cytosine Count

1539461 bp

Genome Length

5391736 bp

Protein-coding Genes

4894 genes

Non-Coding Genes

213 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pullulanase secretion protein pulhSAMEA3649717_03386Not AvailableNegative3590215 - 359072418712.4
pullulanase g proteinSAMEA3649717_03387Not AvailableNegative3590724 - 359114615401.5
general secretion pathway protein fSAMEA3649717_03388Not AvailableNegative3591167 - 359238144181.8
general secretion pathway protein eSAMEA3649717_03389Not AvailableNegative3592383 - 359387655197.0
general secretion pathway protein dSAMEA3649717_03390Not AvailableNegative3593873 - 359582869523.0
general secretion pathway protein cSAMEA3649717_03391Not AvailableNegative3595856 - 359669830219.8
pullulanaseSAMEA3649717_03392Not AvailablePositive3597005 - 3600313119167.0
pullulanase-specific type ii secretion system component bSAMEA3649717_03393Not AvailablePositive3600570 - 360112719872.7
penicillin-binding protein 1bSAMEA3649717_03394Not AvailablePositive3602128 - 360468095033.8
ferrichrome outer membrane transporterSAMEA3649717_03395Not AvailablePositive3604915 - 360712281385.3

Displaying genes 3471 – 3480 of 5107 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total