Klebsiella pneumoniae strain EuSCAPE_ES107

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES107 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. It thrives optimally at 37°C and falls within the mesophilic temperature range. EuSCAPE_ES107 is associated with a diverse range of hosts, including Homo sapiens, various birds (Phasianidae and Gallus gallus), mammals (such as Canis lupus familiaris, Sus scrofa, and Equidae), as well as amphibians and plants (Viridiplantae). This wide host range suggests a versatile ecological adaptability and significant potential for cross-species transmission. The strain is known to cause a variety of serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. Additionally, it is associated with conditions such as intra-abdominal infections, liver abscesses, and neonatal sepsis. These pathogenic effects highlight the strain's relevance in clinical microbiology and public health. Despite its pathogenic potential, K. pneumoniae EuSCAPE_ES107 is also noted to have a free-living biotic relationship, which may imply its role in environmental microbiomes. The presence of this organism in various ecological niches, combined with its ability to cause significant human infections, underscores the importance of monitoring and understanding its behavior in both clinical and environmental contexts. Its adaptability to various hosts and settings exemplifies the challenges in managing infections caused by such multi-host pathogens.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES107

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES107
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES107 genome assembly,

Gene Summary

Adenine Count

1273334 bp

Thymine Count

1269162 bp

Guanine Count

1644712 bp

Cytosine Count

1663252 bp

Genome Length

5850460 bp

Protein-coding Genes

5312 genes

Non-Coding Genes

176 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
4-hydroxyphenylacetate permeaseSAMEA3649423_03617Not AvailablePositive3890016 - 389137449819.9
4-hydroxyphenylacetate catabolism regulatory protein hpaaSAMEA3649423_03618Not AvailablePositive3891384 - 389227434269.7
4-hydroxyphenylacetate 3-monooxygenaseSAMEA3649423_03619Not AvailablePositive3892500 - 389406258889.2
4-hydroxyphenylacetate 3-monooxygenaseSAMEA3649423_03620Not AvailablePositive3894082 - 389459418421.5
ascbf operon repressorSAMEA3649423_03621Not AvailableNegative3894669 - 389549031166.2
uncharacterised proteinSAMEA3649423_03622Not AvailableNegative3895507 - 389613024026.7
carbon starvation protein aSAMEA3649423_03623Not AvailablePositive3896515 - 389866577182.4
small protein yjixSAMEA3649423_03624Not AvailablePositive3898775 - 38989787697.14
cobw/p47k family proteinSAMEA3649423_03625Not AvailablePositive3898990 - 389994635731.8
exported proteinSAMEA3649423_03626Not AvailablePositive3900338 - 390088318602.1

Displaying genes 3721 – 3730 of 5488 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total