Klebsiella pneumoniae strain EuSCAPE_GR154

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR154 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically forms cells in chains, pairs, or as singles. Its optimal growth temperature is 37°C, which aligns with its classification as mesophilic. K. pneumoniae EuSCAPE_GR154 is associated with a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and vertebrates. This broad host range highlights its ecological versatility. The bacterium is involved in numerous health effects, particularly in humans, where it is known to cause infections such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. As a free-living organism, K. pneumoniae EuSCAPE_GR154 plays a significant role in the microbiome of its hosts but also poses risks as a human pathogen. Its ability to cause severe health issues underscores the importance of monitoring and understanding its epidemiology and pathogenic mechanisms. The presence of a single replicon and double membrane structure is characteristic of its cellular organization, which may contribute to its adaptability and resilience in various environments. Understanding the traits of this strain can aid in developing effective treatment strategies and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR154

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR154
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR154 genome assembly,

Gene Summary

Adenine Count

1260077 bp

Thymine Count

1267088 bp

Guanine Count

1680749 bp

Cytosine Count

1650286 bp

Genome Length

5858200 bp

Protein-coding Genes

5254 genes

Non-Coding Genes

348 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein of uncharacterised function (duf2509)SAMEA3649773_00517Not AvailablePositive509365 - 50977214765.0
prepilin peptidase dependent protein cSAMEA3649773_00518Not AvailablePositive509757 - 51008011998.8
exodeoxyribonuclease v subunit gammaSAMEA3649773_00519Not AvailablePositive510093 - 513470128883.0
protease iiiSAMEA3649773_00520Not AvailablePositive513591 - 516476107461.0
exonuclease v subunit betaSAMEA3649773_00521Not AvailablePositive516473 - 520009132910.0
exodeoxyribonuclease v subunit alphaSAMEA3649773_00522Not AvailablePositive520006 - 52185066526.3
uncharacterised proteinSAMEA3649773_00523Not AvailableNegative521908 - 52222811798.8
n-acetylglutamate synthaseSAMEA3649773_00524Not AvailableNegative522458 - 52378949478.6
n-acetylmuramoyl-l-alanine amidaseSAMEA3649773_00525Not AvailablePositive524017 - 52527045468.9
l-threonine 3-o-phosphate decarboxylaseSAMEA3649773_00526Not AvailablePositive525288 - 52636440083.5

Displaying genes 801 – 810 of 5602 in total

Metabolites

1429 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000232(4S)-perillyl alcoholC10H16OChemical structure of (4S)-perillyl alcoholNot available
Average152.237Da
Monoisotopic152.1201151Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da

Displaying 1–10 of 1429 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total