Klebsiella pneumoniae strain EuSCAPE_GR153

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR153 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism as a chemoheterotroph. It can thrive in various environments, being host-associated and capable of existing in chains, pairs, or as single cells. This strain is notable for its mobility, facilitated by the presence of flagella, and has an optimal growth temperature of 37°C, categorizing it as mesophilic. EuSCAPE_GR153 is significant in clinical microbiology due to its association with a range of serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its pathogenicity extends to other hosts, such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), among others. This broad host range indicates a versatile ecological adaptability, allowing it to colonize various environments and organisms. The strain is nonsporulating and possesses a single replicon and two membranes, which are characteristic features of Gram-negative bacteria. Given its ability to cause severe infections, including septicemia and neonatal sepsis, Klebsiella pneumoniae strain EuSCAPE_GR153 underscores the importance of monitoring and understanding the dynamics of pathogenic bacteria in clinical settings. Its role in human health and disease highlights the interconnectedness of microbial life and the necessity for vigilance in public health efforts, particularly concerning antibiotic resistance and infection control measures.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR153

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR153
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR153 genome assembly,

Gene Summary

Adenine Count

1199042 bp

Thymine Count

1211404 bp

Guanine Count

1618099 bp

Cytosine Count

1593356 bp

Genome Length

5621901 bp

Protein-coding Genes

5091 genes

Non-Coding Genes

190 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive3229681 - 3229693Not Available
GlutaredoxinSAMEA3649772_03016Not AvailablePositive3241029 - 32412929839.71
inner membrane proteinSAMEA3649772_03017Not AvailableNegative3241299 - 324168214113.8
trka, potassium channel-family proteinSAMEA3649772_03018Not AvailablePositive3241949 - 324363460420.1
uncharacterised proteinSAMEA3649772_03019Not AvailableNegative3243856 - 32440778268.73
P2 gpogr-like protein (acttivation of late gene expression)SAMEA3649772_03020Not AvailableNegative3244235 - 32444508093.62
Tail proteinSAMEA3649772_03021Not AvailableNegative3244518 - 324478710152.0
Tail proteinSAMEA3649772_03022Not AvailableNegative3245148 - 324560016610.8
Tail proteinSAMEA3649772_03023Not AvailableNegative3245597 - 324608217885.7
Capsid packaging proteinSAMEA3649772_03024Not AvailablePositive3246252 - 324664114640.8

Displaying genes 1 – 10 of 5281 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
SbpCausesPMC10556727
MasldCausesPMC12853991
Urinary tract infectionsCausesPMC12788680
SepticemiaCausesPMC12788680
Abdominal infectionsCausesPMC12788680
Bacterial pneumoniaCausesPMC12788680
Catheter-associated urinary tract infectionCausesPMC2900259
CautiCausesPMC2900259
CystitisCausesPMC4353729
PneumoniaCausesPMC6315841

Displaying health effects 41 – 50 of 53 in total