Klebsiella pneumoniae strain EuSCAPE_RS007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS007 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain exhibits diverse cell arrangements, including chains, pairs, and singles, and possesses flagella, which contributes to its mobility. It thrives optimally at 37°C and falls within a mesophilic temperature range. This bacterium is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan species, indicating its broad ecological presence. Notably, K. pneumoniae strain EuSCAPE_RS007 is recognized for its pathogenicity in humans, causing a range of serious health effects such as bacteremia, urinary tract infections, pneumonia, and other intra-abdominal infections. These infections can lead to severe conditions like sepsis and neonatal sepsis, underscoring the strain's clinical significance. The presence of this strain in both free-living and host-associated environments suggests its adaptability and potential for opportunistic infections in various hosts. Its ability to infect a wide range of species—from mammals to birds and amphibians—highlights its ecological versatility and potential as a zoonotic pathogen. Understanding the biological behavior and pathogenic mechanisms of K. pneumoniae strain EuSCAPE_RS007 is crucial for developing strategies to manage infections, especially in healthcare settings where such pathogens pose significant risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS007 genome assembly,

Gene Summary

Adenine Count

1146446 bp

Thymine Count

1140331 bp

Guanine Count

1533315 bp

Cytosine Count

1519144 bp

Genome Length

5339236 bp

Protein-coding Genes

4916 genes

Non-Coding Genes

193 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Protein of unknown function duf927SAMEA3649813_01922Not AvailablePositive2020522 - 202265777917.0
uncharacterised proteinSAMEA3649813_01923Not AvailablePositive2023000 - 202333512245.2
uncharacterised proteinSAMEA3649813_01924Not AvailableNegative2023384 - 202389618229.7
Phage major capsid proteinSAMEA3649813_01925Not AvailablePositive2024160 - 202532642984.8
Putative prohead proteaseSAMEA3649813_01926Not AvailablePositive2025378 - 202593820928.6
Portal proteinSAMEA3649813_01927Not AvailablePositive2025940 - 202718146391.8
Head-tail connector iiSAMEA3649813_01928Not AvailablePositive2027178 - 202751312410.9
Head-tail connector proteinSAMEA3649813_01929Not AvailablePositive2027510 - 202780911214.5
Hypothetical proteinSAMEA3649813_01930Not AvailablePositive2027809 - 202825217586.8
uncharacterised proteinSAMEA3649813_01931Not AvailablePositive2028245 - 20283976277.46

Displaying genes 11 – 20 of 5109 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total