Klebsiella pneumoniae strain EuSCAPE_RS007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_RS007 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain exhibits diverse cell arrangements, including chains, pairs, and singles, and possesses flagella, which contributes to its mobility. It thrives optimally at 37°C and falls within a mesophilic temperature range. This bacterium is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan species, indicating its broad ecological presence. Notably, K. pneumoniae strain EuSCAPE_RS007 is recognized for its pathogenicity in humans, causing a range of serious health effects such as bacteremia, urinary tract infections, pneumonia, and other intra-abdominal infections. These infections can lead to severe conditions like sepsis and neonatal sepsis, underscoring the strain's clinical significance. The presence of this strain in both free-living and host-associated environments suggests its adaptability and potential for opportunistic infections in various hosts. Its ability to infect a wide range of species—from mammals to birds and amphibians—highlights its ecological versatility and potential as a zoonotic pathogen. Understanding the biological behavior and pathogenic mechanisms of K. pneumoniae strain EuSCAPE_RS007 is crucial for developing strategies to manage infections, especially in healthcare settings where such pathogens pose significant risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_RS007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_RS007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_RS007 genome assembly,

Gene Summary

Adenine Count

1146446 bp

Thymine Count

1140331 bp

Guanine Count

1533315 bp

Cytosine Count

1519144 bp

Genome Length

5339236 bp

Protein-coding Genes

4916 genes

Non-Coding Genes

193 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutamate 5-kinaseSAMEA3649813_00006Not AvailableNegative4854 - 595739119.1
outer membrane pore protein eSAMEA3649813_00007Not AvailablePositive6247 - 729938725.9
lipoprotein nlpcSAMEA3649813_00008Not AvailableNegative7344 - 780517678.9
drug/metabolite transporter permeaseSAMEA3649813_00009Not AvailablePositive8323 - 919230814.5
phosphoserine phosphataseSAMEA3649813_00010Not AvailablePositive9288 - 995324324.2
uncharacterised proteinSAMEA3649813_00011Not AvailablePositive9966 - 1075726488.9
phosphonate abc transporter permeaseSAMEA3649813_00012Not AvailableNegative11363 - 1224732816.8
putative inner membrane permease of abc transporterSAMEA3649813_00013Not AvailableNegative12244 - 1311632284.1
phosphonate abc transporter substrate-binding proteinSAMEA3649813_00014Not AvailableNegative13183 - 1412133604.3
phosphonate transport atp-binding proteinSAMEA3649813_00015Not AvailableNegative14144 - 1498630629.1

Displaying genes 141 – 150 of 5109 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total