Klebsiella pneumoniae strain EuSCAPE_GR151

Klebsiella pneumoniae strain EuSCAPE_GR151 is a significant pathogen with a broad host range that includes Homo sapiens, various domestic animals, and several vertebrate species. This bacterium is classified as a Gram-negative, rod-shaped organism that typically exists in chains, pairs, or as single cells. It is a facultative anaerobe capable of thriving in diverse environments, primarily utilizing chemoheterotrophic metabolism. The strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, facilitating its role as a human pathogen. Klebsiella pneumoniae EuSCAPE_GR151 possesses flagella, indicating mobility, which may contribute to its virulence and ability to colonize different tissues. Importantly, it has a complex biotic relationship, being free-living but capable of causing a range of serious health conditions. These include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections, among others. With a single replicon and a double membrane structure, this strain is well-equipped for survival in host-associated habitats. Its pathogenicity in humans is of particular concern, as it can lead to severe infections such as neonatal sepsis and pyogenic liver abscesses. The diverse range of hosts it can infect highlights its ecological adaptability and potential for zoonotic transmission. This adaptability may play a crucial role in its persistence and spread in both human populations and animal reservoirs, emphasizing the importance of monitoring and controlling infections caused by this strain.