Klebsiella pneumoniae strain EuSCAPE_GR135

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR135 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it a chemoheterotroph. This strain is characterized by its ability to thrive at an optimal temperature of 37°C, placing it within the mesophilic temperature range. It is motile and possesses flagella, allowing for movement. The bacterium can be found in various arrangements, including chains, pairs, and singles, and possesses a single replicon and two membranes. EuSCAPE_GR135 is primarily host-associated and has been identified in a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Danio rerio (zebrafish), and various mammals and plants. This broad host range indicates a significant ecological adaptability and interaction with diverse biological systems. The health effects associated with this strain are extensive, encompassing conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity primarily affects humans, leading to serious health complications that can arise from infections in different body systems. Given its role in human health and its presence across multiple hosts, Klebsiella pneumoniae strain EuSCAPE_GR135 exemplifies the complexities of microbial interactions within host environments. Its capacity to cause a wide array of infections highlights the importance of understanding its biology and ecology, particularly in relation to antibiotic resistance and public health implications. This strain serves as a reminder of the interconnectedness of pathogens and their hosts in both health and disease contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR135

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR135
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR135 genome assembly,

Gene Summary

Adenine Count

1203199 bp

Thymine Count

1201016 bp

Guanine Count

1589612 bp

Cytosine Count

1616147 bp

Genome Length

5609974 bp

Protein-coding Genes

5132 genes

Non-Coding Genes

224 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
colicin i receptorSAMEA3649754_00575Not AvailableNegative601390 - 60336372971.8
lysine-specific permeaseSAMEA3649754_00576Not AvailableNegative603862 - 60533153729.1
lysr family transcriptional regulator yeieSAMEA3649754_00577Not AvailableNegative605510 - 60637631952.8
membrane protein yeihSAMEA3649754_00578Not AvailablePositive606642 - 60769136853.5
endonuclease ivSAMEA3649754_00579Not AvailablePositive607764 - 60861831202.9
pts system fructose-specific transporter subunit iibSAMEA3649754_00580Not AvailableNegative608670 - 61036457552.8
1-phosphofructokinaseSAMEA3649754_00581Not AvailableNegative610381 - 61131933844.6
fructose-specific phosphocarrier protein hprSAMEA3649754_00582Not AvailableNegative611320 - 61245039505.9
sugar efflux transporter bSAMEA3649754_00583Not AvailablePositive612787 - 61396842879.7
proteinase inhibitorSAMEA3649754_00584Not AvailableNegative614008 - 6142629084.17

Displaying genes 751 – 760 of 5356 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total