Klebsiella pneumoniae strain EuSCAPE_GR078

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR078 is a Gram-negative, rod-shaped bacterium that exhibits a range of pathogenic effects in humans and various other hosts. This strain is classified as a facultative anaerobe and utilizes a chemoheterotrophic energy source. It typically exists in chains, pairs, or as single cells, indicating a versatile adaptation for its growth and survival in diverse environments. Notably, K. pneumoniae EuSCAPE_GR078 possesses flagella, which contribute to its mobility. This characteristic is essential for its ability to colonize different hosts, including Homo sapiens, Gallus gallus, and other Metazoa and Viridiplantae, as well as several animal species such as Canis lupus familiaris and Sus scrofa. The bacterium thrives optimally at 37°C, within a mesophilic temperature range, and has a unique cellular structure comprising two membranes and a single replicon. K. pneumoniae is known for its pathogenicity, causing a variety of infections such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. The bacterium’s ability to affect multiple hosts and cause severe health implications highlights its ecological role as an opportunistic pathogen. This strain's free-living nature and adaptability reinforce the importance of monitoring its spread and impact on public health, particularly in relation to its association with serious infections in humans and other animals. Understanding the ecological dynamics of K. pneumoniae EuSCAPE_GR078 is essential for developing effective treatment and prevention strategies against its associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR078

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR078
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR078 genome assembly,

Gene Summary

Adenine Count

1175996 bp

Thymine Count

1174795 bp

Guanine Count

1571124 bp

Cytosine Count

1577754 bp

Genome Length

5499669 bp

Protein-coding Genes

4994 genes

Non-Coding Genes

182 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3649697_00084Not AvailableNegative96143 - 9662518008.5
Putative major tail proteinSAMEA3649697_00085Not AvailableNegative96680 - 9785240970.6
Trna-met;Not AvailableNot AvailablePositive97146 - 97222Not Available
Putative tail terminator proteinSAMEA3649697_00086Not AvailableNegative97876 - 9826813974.7
Hypothetical proteinSAMEA3649697_00087Not AvailableNegative98265 - 9881620185.9
Hypothetical proteinSAMEA3649697_00088Not AvailableNegative98818 - 9920113710.1
uncharacterised proteinSAMEA3649697_00089Not AvailableNegative99173 - 9946910948.1
Putative head-tail joining proteinSAMEA3649697_00090Not AvailableNegative99471 - 9988114469.4
Hypothetical proteinSAMEA3649697_00091Not AvailableNegative99885 - 1000977665.87
Putative coat proteinSAMEA3649697_00092Not AvailableNegative100137 - 10127338865.9

Displaying genes 11 – 20 of 5176 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total