Klebsiella pneumoniae strain EuSCAPE_ES150

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES150 is a notable pathogenic bacterium primarily associated with human hosts, but it exhibits a wide range of potential hosts, including various species of animals and plants. This Gram-negative, rod-shaped bacterium is a facultative anaerobe and utilizes chemoheterotrophic metabolism for energy. It is capable of existing in multiple cell arrangements, including chains, pairs, and singles, and possesses flagella, which confer mobility. The strain is mesophilic, with an optimal growth temperature of 37°C, and it has a unique cellular structure characterized by two membranes and a single replicon. EuSCAPE_ES150 is free-living yet is known to be pathogenic in humans, causing a variety of serious health issues, such as pneumonia, urinary tract infections, bloodstream infections, and sepsis. The strain is associated with numerous clinical conditions, including bacteremia, pyogenic liver abscesses, and neonatal sepsis, indicating its potential virulence and adaptability to various environments within the host. Understanding the ecological role and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_ES150 underscores the importance of monitoring and managing its spread, particularly in healthcare settings where it can lead to significant morbidity and mortality. The strain's ability to thrive in diverse habitats and infect multiple hosts highlights its role as a significant opportunistic pathogen in both human health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES150

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES150
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES150 genome assembly,

Gene Summary

Adenine Count

1282850 bp

Thymine Count

1283184 bp

Guanine Count

1676422 bp

Cytosine Count

1695466 bp

Genome Length

5937922 bp

Protein-coding Genes

5189 genes

Non-Coding Genes

336 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3649466_02998Not AvailablePositive3238314 - 323880518182.8
uncharacterised proteinSAMEA3649466_02999Not AvailablePositive3239050 - 324040852289.2
Tail fiber proteinSAMEA3649466_03000Not AvailableNegative3240562 - 324165938986.4
Hypothetical proteinSAMEA3649466_03001Not AvailableNegative3241659 - 32418718078.39
Tail proteinSAMEA3649466_03002Not AvailableNegative3241868 - 3244894107841.0
Baseplate assembly proteinSAMEA3649466_03003Not AvailableNegative3244884 - 324580733017.9
Baseplate assembly proteinSAMEA3649466_03004Not AvailableNegative3245809 - 324615912475.9
Baseplate assembly proteinSAMEA3649466_03005Not AvailableNegative3246156 - 324674320646.4
Virion morphogenesis proteinSAMEA3649466_03006Not AvailableNegative3246740 - 324737523833.6
Tail proteinSAMEA3649466_03007Not AvailableNegative3247372 - 324783917465.9

Displaying genes 61 – 70 of 5525 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total