Klebsiella pneumoniae strain EuSCAPE_ES172

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES172 is a Gram-negative bacterium exhibiting a rod shape and capable of mobility due to the presence of flagella. Characterized as a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, making it versatile in different habitats. This strain is primarily host-associated and displays a biotic relationship that is free-living, indicating its ability to survive outside of a host under certain conditions. As a chemoheterotroph, K. pneumoniae EuSCAPE_ES172 derives its energy from organic compounds, contributing to its role in various ecological niches. The optimal growth temperature for this strain is 37°C, aligning with the average body temperature of many warm-blooded hosts. It can exist in different arrangements, such as chains, pairs, and singles. This strain is of significant medical concern due to its association with a wide range of health effects in humans, including bacteremia, urinary tract infections, pneumonia, and various other severe infections. It has been implicated in conditions like sepsis, neonatal sepsis, and emphysematous pyelonephritis, demonstrating its pathogenicity in humans. K. pneumoniae EuSCAPE_ES172's ability to infect a variety of hosts, including mammals, birds, and even plants, suggests an ecological flexibility that may enhance its survival and transmission in diverse environments. Such adaptability underscores the importance of monitoring this strain in clinical settings to prevent and control its spread, particularly in light of its extensive pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES172

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES172
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES172 genome assembly,

Gene Summary

Adenine Count

1202585 bp

Thymine Count

1202737 bp

Guanine Count

1594383 bp

Cytosine Count

1603075 bp

Genome Length

5602780 bp

Protein-coding Genes

5061 genes

Non-Coding Genes

231 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative tail terminator proteinSAMEA3649488_02520Not AvailableNegative2739547 - 273993913988.7
Hypothetical proteinSAMEA3649488_02521Not AvailableNegative2739936 - 274048720184.9
Hypothetical proteinSAMEA3649488_02522Not AvailableNegative2740489 - 274087213710.1
uncharacterised proteinSAMEA3649488_02523Not AvailableNegative2740859 - 27410928507.3
Hypothetical proteinSAMEA3649488_02524Not AvailableNegative2741102 - 27413569459.31
Putative head-tail joining proteinSAMEA3649488_02525Not AvailableNegative2741358 - 274175314377.0
Major capsid proteinSAMEA3649488_02526Not AvailableNegative2742075 - 274302834215.2
Hypothetical proteinSAMEA3649488_02527Not AvailableNegative2743039 - 274382427877.8
Head morphogenesis proteinSAMEA3649488_02528Not AvailableNegative2743909 - 274502141230.8
Putative portal vertex proteinSAMEA3649488_02529Not AvailableNegative2745005 - 274640551767.6

Displaying genes 11 – 20 of 5292 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total