Klebsiella pneumoniae strain EuSCAPE_ES133

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES133 is a Gram-negative, rod-shaped bacterium that primarily associates with various hosts, including humans (Homo sapiens), domesticated animals, and some plant species. It is classified as a facultative anaerobe, enabling it to thrive in both the presence and absence of oxygen. This strain exhibits mobility, facilitated by the presence of flagella, and typically grows in chains, pairs, or as singles. As a chemoheterotroph, K. pneumoniae strain EuSCAPE_ES133 utilizes organic compounds for energy. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, suggesting a strong affinity for human hosts. The bacterium has a biotic relationship characterized as free-living. K. pneumoniae strain EuSCAPE_ES133 has been implicated in a range of health issues, particularly in humans. It is known to cause serious infections such as bacteremia, urinary tract infections, pneumonia, and more severe conditions like sepsis and meningitis. The strain’s pathogenicity is of significant concern, given its potential to lead to various complications, including liver abscesses and pulmonary infections. Understanding the ecological presence and pathogenic capabilities of K. pneumoniae strain EuSCAPE_ES133 is crucial, particularly in clinical settings. Its ability to infect a wide range of hosts, alongside its diverse health impacts, highlights the importance of monitoring this strain in both human and veterinary medicine to mitigate health risks associated with its pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES133

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES133
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES133 genome assembly,

Gene Summary

Adenine Count

1186045 bp

Thymine Count

1187885 bp

Guanine Count

1585983 bp

Cytosine Count

1589732 bp

Genome Length

5549645 bp

Protein-coding Genes

5099 genes

Non-Coding Genes

153 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug translocase mdfaSAMEA3649449_01353Not AvailableNegative1462791 - 146402344540.9
permeaseSAMEA3649449_01354Not AvailablePositive1464351 - 146494422016.3
deoxyribose operon repressorSAMEA3649449_01355Not AvailablePositive1465046 - 146580428003.8
d-alanyl-d-alanine carboxypeptidase fraction cSAMEA3649449_01356Not AvailableNegative1465843 - 146705443808.9
glutathione s-transferaseSAMEA3649449_01357Not AvailablePositive1469360 - 146998623459.2
soluble aldose sugar dehydrogenase, pqq-dependentSAMEA3649449_01358Not AvailableNegative1469989 - 147109839942.9
biofilm formation regulatory protein bssrSAMEA3649449_01359Not AvailableNegative1471214 - 147159714343.5
sucrose permeaseSAMEA3649449_01360Not AvailablePositive1471976 - 147321746126.1
ribosomal protein s12p methylthiotransferaseSAMEA3649449_01361Not AvailablePositive1473450 - 147477549570.7
glutathione abc transporter permease gsidSAMEA3649449_01362Not AvailableNegative1475456 - 147636732798.7

Displaying genes 1361 – 1370 of 5252 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total