Klebsiella pneumoniae strain EuSCAPE_ES137

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES137 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain exhibits a versatile cell arrangement, forming chains, pairs, and singles, and possesses flagella, allowing for mobility. EuSCAPE_ES137 has a mesophilic temperature range, with an optimal growth temperature of 37°C, which is characteristic of many pathogens that thrive in human body conditions. This bacterium is primarily associated with various hosts, including Homo sapiens, Gallus gallus, and other metazoans, as well as certain plants and animals such as Danio rerio and Ovis aries. Its pathogenic potential in humans is significant, as it is implicated in a wide range of infections, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is nonsporulating and maintains a biotic relationship characterized as free-living, suggesting adaptability in diverse environments. The presence of only one replicon and two membranes indicates a streamlined genomic structure, which may contribute to its pathogenicity and ability to survive in host-associated habitats. The broad spectrum of health effects associated with Klebsiella pneumoniae strain EuSCAPE_ES137 highlights its importance in clinical microbiology, emphasizing the need for continued surveillance and research to understand its role in human health and disease dynamics. The strain's adaptability and pathogenicity underscore the ecological implications of its presence in various ecosystems, particularly concerning public health and the management of infectious diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES137

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES137
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES137 genome assembly,

Gene Summary

Adenine Count

1434893 bp

Thymine Count

1431269 bp

Guanine Count

1841067 bp

Cytosine Count

1854364 bp

Genome Length

6561593 bp

Protein-coding Genes

5566 genes

Non-Coding Genes

280 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3649453_01959Not AvailablePositive2089842 - 209068430782.7
enhanced serine sensitivity protein ssebSAMEA3649453_01960Not AvailableNegative2090755 - 209153128257.8
aminopeptidase bSAMEA3649453_01961Not AvailableNegative2091630 - 209291646221.6
fes assembly protein iscxSAMEA3649453_01962Not AvailableNegative2092987 - 20931877745.94
ferredoxinSAMEA3649453_01963Not AvailableNegative2093189 - 209352412342.4
chaperone protein hscaSAMEA3649453_01964Not AvailableNegative2093526 - 209537665399.2
chaperone protein hscbSAMEA3649453_01965Not AvailableNegative2095392 - 209590719825.4
iron binding protein isca for iron-sulfur cluster assemblySAMEA3649453_01966Not AvailableNegative2095982 - 209630511449.5
iron-sulfur cluster assembly scaffold protein iscuSAMEA3649453_01967Not AvailableNegative2096323 - 209670913807.3
cysteine desulfuraseSAMEA3649453_01968Not AvailableNegative2096736 - 209795045059.1

Displaying genes 2041 – 2050 of 5846 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total